Big biomedical data as the key resource for discovery science.

Modern biomedical data collection is generating exponentially more data in a multitude of formats. This flood of complex data poses significant opportunities to discover and understand the critical interplay among such diverse domains as genomics, proteomics, metabolomics, and phenomics, including i...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of the American Medical Informatics Association Vol. 22; no. 6; pp. 1126 - 1132
Autores principales: Toga, Arthur W., Foster, Ian, Kesselman, Carl, Madduri, Ravi, Chard, Kyle, Deutsch, Eric W., Price, Nathan D., Glusman, Gustavo, Heavner, Benjamin D., Dinov, Ivo D., Ames, Joseph, Van Horn, John, Kramer, Roger, Hood, Leroy
Formato: Journal Article
Publicado: Oxford University Press / USA Nov2015
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=110875721&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 110875721
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        10675027
        FZ9
      jtl: Journal of the American Medical Informatics Association
      issn: 10675027
      maglogo: N
    pubinfo:
      dt: Nov2015
      vid: 22
      iid: 6
      pid: 622
      pub: Oxford University Press / USA
    artinfo:
      ui:
        110875721
        110875721
        NLM26198305
        10.1093/jamia/ocv077
        NLM26198305
        PMC5009918 [Available on 11/01/16]
        110875721
      ppf: 1126
      ppct: 6
      formats:
      tig:
        atl: Big biomedical data as the key resource for discovery science.
      aug:
        au:
          Toga, Arthur W.
          Foster, Ian
          Kesselman, Carl
          Madduri, Ravi
          Chard, Kyle
          Deutsch, Eric W.
          Price, Nathan D.
          Glusman, Gustavo
          Heavner, Benjamin D.
          Dinov, Ivo D.
          Ames, Joseph
          Van Horn, John
          Kramer, Roger
          Hood, Leroy
        affil: Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, USA
      sug:
        subj:
          Data Collection
          Research, Medical
          Neurosciences
          United States
          National Institutes of Health (U.S.)
          Scales
      ab: Modern biomedical data collection is generating exponentially more data in a multitude of formats. This flood of complex data poses significant opportunities to discover and understand the critical interplay among such diverse domains as genomics, proteomics, metabolomics, and phenomics, including imaging, biometrics, and clinical data. The Big Data for Discovery Science Center is taking an "-ome to home" approach to discover linkages between these disparate data sources by mining existing databases of proteomic and genomic data, brain images, and clinical assessments. In support of this work, the authors developed new technological capabilities that make it easy for researchers to manage, aggregate, manipulate, integrate, and model large amounts of distributed data. Guided by biological domain expertise, the Center's computational resources and software will reveal relationships and patterns, aiding researchers in identifying biomarkers for the most confounding conditions and diseases, such as Parkinson's and Alzheimer's.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N