Functional deterioration from the premorbid period to 2 years after the first episode of psychosis in early-onset psychosis.
The aim of the study was to analyze changes in functional adjustment from childhood to 2 years after the first episode of psychosis (FEP) in patients with early-onset schizophrenia spectrum disorders (SSD) and affective psychoses (AFP) and a good or intermediate level of premorbid adjustment. We fol...
| Publicado en: | European Child & Adolescent Psychiatry Vol. 24; no. 12; pp. 1447 - 1460 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Dec2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=111003896&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 111003896 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10188827 EJ3 jtl: European Child & Adolescent Psychiatry issn: 10188827 maglogo: N pubinfo: dt: Dec2015 vid: 24 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 111003896 111003896 111003896 10.1007/s00787-015-0693-5 NLM25726022 111003896 ppf: 1447 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Functional deterioration from the premorbid period to 2 years after the first episode of psychosis in early-onset psychosis. aug: au: Del Rey-Mejías, Ángel Fraguas, David Díaz-Caneja, Covadonga Pina-Camacho, Laura Castro-Fornieles, Josefina Baeza, Inmaculada Espliego, Ana Merchán-Naranjo, Jessica González-Pinto, Ana Serna, Elena Payá, Beatriz Graell, Montserrat Arango, Celso Parellada, Mara affil: Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Marañón, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Ibiza 43 28009 Madrid Spain sug: subj: Morbidity Psychotic Disorders Child Development Schizophrenia, Childhood Prospective Studies Human Child Adolescence Male Female Descriptive Statistics Data Analysis Software Odds Ratio Confidence Intervals Analysis of Covariance Multivariate Analysis Scales Funding Source Child: 6-12 years Adolescent: 13-18 years Male Female ab: The aim of the study was to analyze changes in functional adjustment from childhood to 2 years after the first episode of psychosis (FEP) in patients with early-onset schizophrenia spectrum disorders (SSD) and affective psychoses (AFP) and a good or intermediate level of premorbid adjustment. We followed 106 adolescents (aged 12-17 years) with FEP for 2 years after recruitment. Premorbid adjustment in childhood was assessed in 98 patients with the childhood subscale of the Cannon-Spoor Premorbid Adjustment Scale (c-PAS). Global functioning was assessed 2 years after the FEP with the Children's Global Assessment Scale (c-GAS) or the Global Assessment of Functioning scale (GAF), as appropriate. Functional deterioration was defined as a downward shift in the level of functional adjustment from childhood to 2 years after the FEP. In patients with good or intermediate premorbid adjustment, functional deterioration was observed in 28.2 % (26.5 % of the AFP group, 29.4 % of the SSD group). Longer duration of untreated psychosis (Beta = 0.01; P = 0.01) and higher symptom severity at the FEP, as measured with the Clinical Global Impression Scale (Beta = 1.12; P = 0.02), significantly predicted the presence of functional deterioration, accounting for 21.4 % of the variance. Irrespective of diagnosis (SSD or AFP), almost one-third of adolescents with FEP and good or intermediate premorbid adjustment showed functional deterioration from the premorbid period to 2 years after the FEP. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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