Replication and Comparison of the Newly Proposed ADOS-2, Module 4 Algorithm in ASD Without ID: A Multi-site Study.
Recent updates have been proposed to the Autism Diagnostic Observation Schedule-2 Module 4 diagnostic algorithm. This new algorithm, however, has not yet been validated in an independent sample without intellectual disability (ID). This multi-site study compared the original and revised algorithms i...
| Published in: | Journal of Autism & Developmental Disorders Vol. 45; no. 12; pp. 3919 - 3932 |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Springer Nature
Dec2015
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=111070562&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 111070562 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Dec2015 vid: 45 iid: 12 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 111070562 111070562 111070562 10.1007/s10803-015-2586-3 NLM26385796 111070562 ppf: 3919 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Replication and Comparison of the Newly Proposed ADOS-2, Module 4 Algorithm in ASD Without ID: A Multi-site Study. aug: au: Pugliese, Cara Kenworthy, Lauren Bal, Vanessa Wallace, Gregory Yerys, Benjamin Maddox, Brenna White, Susan Popal, Haroon Armour, Anna Miller, Judith Herrington, John Schultz, Robert Martin, Alex Anthony, Laura affil: Center for Autism Spectrum Disorders & Children's National Research Institute, Children's National Health System, Washington USA sug: subj: Autism Spectrum Disorder Diagnosis Human Funding Source Replication Studies Case Control Studies Multicenter Studies Sensitivity and Specificity Algorithms United States Male Female Adult Middle Age Aged Descriptive Statistics Chi Square Test Nonparametric Statistics Scales Clinical Assessment Tools Intelligence Tests Psychological Tests Questionnaires Behavior Rating Scales Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Recent updates have been proposed to the Autism Diagnostic Observation Schedule-2 Module 4 diagnostic algorithm. This new algorithm, however, has not yet been validated in an independent sample without intellectual disability (ID). This multi-site study compared the original and revised algorithms in individuals with ASD without ID. The revised algorithm demonstrated increased sensitivity, but lower specificity in the overall sample. Estimates were highest for females, individuals with a verbal IQ below 85 or above 115, and ages 16 and older. Best practice diagnostic procedures should include the Module 4 in conjunction with other assessment tools. Balancing needs for sensitivity and specificity depending on the purpose of assessment (e.g., clinical vs. research) and demographic characteristics mentioned above will enhance its utility. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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