Medication persistence in older women with osteoporosis: a pilot study.

Summary: Most osteoporosis patients stop their medications before they should. Side effects are the most common reason patients in this sample stopped their medication before they told their physician. Physicians should use shared decision-making and discuss side effects of osteoporosis medications...

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Published in:Osteoporosis International Vol. 26; no. 12; pp. 2883 - 2889
Main Authors: Gillette, C., Howerton, D., Williams, B., Mahmood, M.
Format: research tables/charts Journal Article
Published: Springer Nature Dec2015
Online Access:View this record in EBSCOhost
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      jtl: Osteoporosis International
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      dt: Dec2015
      vid: 26
      iid: 12
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00198-015-3242-7
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        atl: Medication persistence in older women with osteoporosis: a pilot study.
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        au:
          Gillette, C.
          Howerton, D.
          Williams, B.
          Mahmood, M.
        affil: Department of Pharmacy Practice, Administration, and Research, Marshall University School of Pharmacy, 1 John Marshall Dr. Huntington 25755 USA
      sug:
        subj:
          Osteoporosis Drug Therapy
          Patient Compliance
          Osteoporosis Epidemiology
          Human
          Female
          Aged
          Aged, 80 and Over
          Drugs Adverse Effects
          Middle Age
          Cross Sectional Studies Utilization
          Surveys
          World Wide Web
          Academic Medical Centers
          Data Analysis Software Utilization
          Descriptive Statistics
          T-Tests Utilization
          Chi Square Test Utilization
          Kruskal-Wallis Test Utilization
          West Virginia
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
      ab: Summary: Most osteoporosis patients stop their medications before they should. Side effects are the most common reason patients in this sample stopped their medication before they told their physician. Physicians should use shared decision-making and discuss side effects of osteoporosis medications with their patients and explain the risks of the medications. Introduction: The aims of this study were to (a) qualitatively examine reasons for medication non-persistence in osteoporosis, and (b) investigate how medication non-persistence in osteoporosis is associated with outcome expectations, self-efficacy, trust in physicians, and health locus of control. Methods: Subjects were recruited from online support groups to answer an anonymous online survey. Subjects were eligible if they (a) were female, (b) were at least 40 years of age, (c) self-identify as having osteoporosis, and (d) have taken at least one medication for osteoporosis. During the survey, subjects completed measures of self-efficacy, outcome expectations, trust in physicians generally, health locus of control, and demographic information. Results: Thirty-four subjects completed the online survey and had usable data. Approximately 82 % ( n = 28) of subjects reported discontinuing an osteoporosis medication without first consulting a physician. The most common reason patients discontinued an osteoporosis medication was adverse effects. Subjects were more likely to discontinue their medications when they had poorer outcome expectations on average ( p = 0.01), had lower trust in physicians on average ( p < 0.0001), and had more of a doctors-centered locus of control ( p = 0.03). Self-efficacy, age, insurance, status, and other measures of locus of control were not associated with medication non-persistence. Conclusions: Side effects are a significant concern for women with osteoporosis and may be a cause for medication non-persistence.
      pubtype: Academic Journal
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        research
        tables/charts
        Journal Article
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    exclusion: Y
    language: English
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