Comparative assessment of glucose prediction models for patients with type 1 diabetes mellitus applying sensors for glucose and physical activity monitoring.

The present work presents the comparative assessment of four glucose prediction models for patients with type 1 diabetes mellitus (T1DM) using data from sensors monitoring blood glucose concentration. The four models are based on a feedforward neural network (FNN), a self-organizing map (SOM), a neu...

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Publicado en:Medical & Biological Engineering & Computing Vol. 53; no. 12; pp. 1333 - 1344
Autores principales: Zarkogianni, K., Mitsis, K., Litsa, E., Arredondo, M.-T., Ficο, G., Fioravanti, A., Nikita, K., Ficο, G, Nikita, K S
Formato: Journal Article
Publicado: Springer Nature Dec2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2015
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      pub: Springer Nature
      place: New York, New York
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        atl: Comparative assessment of glucose prediction models for patients with type 1 diabetes mellitus applying sensors for glucose and physical activity monitoring.
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        au:
          Zarkogianni, K.
          Mitsis, K.
          Litsa, E.
          Arredondo, M.-T.
          Ficο, G.
          Fioravanti, A.
          Nikita, K.
          Ficο, G
          Nikita, K S
        affil: Biomedical Simulations and Imaging Laboratory, National Technical University of Athens, 15780 Athens Greece
      sug:
        subj:
          Blood Glucose Analysis
          Monitoring, Physiologic
          Diabetes Mellitus, Type 1 Blood
          Neural Networks (Computer)
          Models, Statistical
          Male
          Adult
          Female
          Middle Age
          Scales
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: The present work presents the comparative assessment of four glucose prediction models for patients with type 1 diabetes mellitus (T1DM) using data from sensors monitoring blood glucose concentration. The four models are based on a feedforward neural network (FNN), a self-organizing map (SOM), a neuro-fuzzy network with wavelets as activation functions (WFNN), and a linear regression model (LRM), respectively. For the development and evaluation of the models, data from 10 patients with T1DM for a 6-day observation period have been used. The models' predictive performance is evaluated considering a 30-, 60- and 120-min prediction horizon, using both mathematical and clinical criteria. Furthermore, the addition of input data from sensors monitoring physical activity is considered and its effect on the models' predictive performance is investigated. The continuous glucose-error grid analysis indicates that the models' predictive performance benefits mainly in the hypoglycemic range when additional information related to physical activity is fed into the models. The obtained results demonstrate the superiority of SOM over FNN, WFNN, and LRM with SOM leading to better predictive performance in terms of both mathematical and clinical evaluation criteria.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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