Errors on interrupter tasks presented during spatial and verbal working memory performance are linearly linked to large-scale functional network connectivity in high temporal resolution resting state fMRI.
The brain is organized into networks composed of spatially separated anatomical regions exhibiting coherent functional activity over time. Two of these networks (the default mode network, DMN, and the task positive network, TPN) have been implicated in the performance of a number of cognitive tasks....
| Publicado en: | Brain Imaging & Behavior Vol. 9; no. 4; pp. 854 - 868 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Dec2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=111244189&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 111244189 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Dec2015 vid: 9 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 111244189 111244189 NLM25563228 10.1007/s11682-014-9347-3 NLM25563228 111244189 ppf: 854 ppct: 14 formats: fmt: @attributes: type: P tig: atl: Errors on interrupter tasks presented during spatial and verbal working memory performance are linearly linked to large-scale functional network connectivity in high temporal resolution resting state fMRI. aug: au: Magnuson, Matthew Thompson, Garth Schwarb, Hillary Pan, Wen-Ju McKinley, Andy Schumacher, Eric Keilholz, Shella Magnuson, Matthew Evan Thompson, Garth John Schumacher, Eric H Keilholz, Shella Dawn affil: Georgia Institute of Technology and Biomedical Engineering, Emory University, 1760 Haygood Dr, HSRB W230 Atlanta USA 30322 sug: subj: Memory Brain Physiology Speech Perception Memory, Short Term Adult Male Adolescence Neuropsychological Tests Female Relaxation Magnetic Resonance Imaging Linear Regression Neural Pathways Physiology Young Adult Clinical Assessment Tools Adult: 19-44 years Adolescent: 13-18 years Male Female ab: The brain is organized into networks composed of spatially separated anatomical regions exhibiting coherent functional activity over time. Two of these networks (the default mode network, DMN, and the task positive network, TPN) have been implicated in the performance of a number of cognitive tasks. To directly examine the stable relationship between network connectivity and behavioral performance, high temporal resolution functional magnetic resonance imaging (fMRI) data were collected during the resting state, and behavioral data were collected from 15 subjects on different days, exploring verbal working memory, spatial working memory, and fluid intelligence. Sustained attention performance was also evaluated in a task interleaved between resting state scans. Functional connectivity within and between the DMN and TPN was related to performance on these tasks. Decreased TPN resting state connectivity was found to significantly correlate with fewer errors on an interrupter task presented during a spatial working memory paradigm and decreased DMN/TPN anti-correlation was significantly correlated with fewer errors on an interrupter task presented during a verbal working memory paradigm. A trend for increased DMN resting state connectivity to correlate to measures of fluid intelligence was also observed. These results provide additional evidence of the relationship between resting state networks and behavioral performance, and show that such results can be observed with high temporal resolution fMRI. Because cognitive scores and functional connectivity were collected on nonconsecutive days, these results highlight the stability of functional connectivity/cognitive performance coupling. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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