Beneficial Effects of Long-Term CPAP Treatment on Sleep Quality and Blood Pressure in Adherent Subjects With Obstructive Sleep Apnea.

BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular diseases. Although CPAP is the first treatment choice for moderate-to-severe OSA, acceptance of and adherence to CPAP remain problematic. High CPAP adherence is generally defined as ≥4 h of use/night for ≥7...

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Publicado en:Respiratory Care Vol. 60; no. 12; pp. 1810 - 1819
Autores principales: Mei-Chen Yang, Yi-Chih Huang, Chou-Chin Lan, Yao-Kuang Wu, Kuo-Feng Huang
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Dec2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2015
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        10.4187/respcare.04199
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        atl: Beneficial Effects of Long-Term CPAP Treatment on Sleep Quality and Blood Pressure in Adherent Subjects With Obstructive Sleep Apnea.
      aug:
        au:
          Mei-Chen Yang
          Yi-Chih Huang
          Chou-Chin Lan
          Yao-Kuang Wu
          Kuo-Feng Huang
        affil: Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Tzu Chi Hospital
      sug:
        subj:
          Sleep Apnea, Obstructive Therapy
          Continuous Positive Airway Pressure
          Patient Compliance
          Blood Pressure Determination
          Sleep
          Quality Improvement
          Retrospective Design
          Human
          Female
          Male
          Cardiovascular Risk Factors
          Sleep Apnea, Obstructive Complications
          Polysomnography
          Anthropometry
          Scales
          Descriptive Statistics
          Data Analysis Software
          P-Value
          Record Review
          Aged
          Adult
          Middle Age
          Aged: 65+ years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular diseases. Although CPAP is the first treatment choice for moderate-to-severe OSA, acceptance of and adherence to CPAP remain problematic. High CPAP adherence is generally defined as ≥4 h of use/night for ≥70% of the nights monitored. We investigated the long-term beneficial effects of CPAP on sleep quality and blood pressure in subjects with moderate-to-sevcrc OSA according to high or low CPAP adherence. METHODS: We retrospectively analyzed 121 subjects with moderate-to-severe OSA from August 2008 to July 2012. These subjects were divided into 3 groups: (1) no CPAP treatment (n = 29), (2) low CPAP adherence (n = 28), and (3) high CPAP adherence (n = 64). All subjects were followed up for at least 1 y. The 3 groups were compared regarding anthro-pometric and polysomnographic variables, presence of cardiovascular comorbidities, and blood pressure at baseline and at the last follow-up. RESULTS: The no-treatment group showed significant increases in oxygen desaturation index and blood pressure. The high-adherence group showed significant improvement in daytime sleepiness, apnea-hypopnea index (AHI), oxygen desaturation index, and blood pressure. Although the AHI was also significantly decreased after CPAP treatment in the low-adherence group, blood pressure remained unchanged. CONCLUSIONS: CPAP treatment had beneficial effects on both sleep quality and blood pressure only in subjects with OSA and high CPAP adherence who used CPAP for ≥4 h/night for ≥70% of nights monitored. Subjects with low CPAP adherence received beneficial effects on AHI, but not blood pressure.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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