Evidence for Autonomic Function and Its Influencing Factors in Subjects With COPD: A Systematic Review.
Cardiovascular autonomic neuropathy is one of the factors implicated in the high morbidity and mortality rate in patients with COPD. Thus, several studies and nonsystematic reviews have increasingly reported autonomic function impairment in these subjects. For a better understanding, this systematic...
| Publicado en: | Respiratory Care Vol. 60; no. 12; pp. 1841 - 1852 |
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| Autores principales: | , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Dec2015
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=111385994&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 111385994 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Dec2015 vid: 60 iid: 12 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 111385994 111385994 111385994 10.4187/respcare.04174 111385994 ppf: 1841 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Evidence for Autonomic Function and Its Influencing Factors in Subjects With COPD: A Systematic Review. aug: au: Mohammed, Jibril Meeus, Mira Derom, Eric Da Silva, Hellen Calders, Patrick affil: Department of Rehabilitation Sciences and Physiotherapy, Ghent University, Ghent, Belgium sug: subj: Autonomic Nervous System Pathology Pulmonary Disease, Chronic Obstructive Physiopathology Systematic Review Human Female Male PubMed Embase Heart Rate Variability Trends Baroreflex Respiratory Function Tests Physical Fitness Physical Activity Body Mass Index P-Value Confidence Intervals Odds Ratio Descriptive Statistics Data Analysis Software Sympathetic Nervous System Severity of Illness Disease Exacerbation Disease Duration Funding Source Female Male ab: Cardiovascular autonomic neuropathy is one of the factors implicated in the high morbidity and mortality rate in patients with COPD. Thus, several studies and nonsystematic reviews have increasingly reported autonomic function impairment in these subjects. For a better understanding, this systematic review was performed to evaluate not only the evidence for autonomic function impairment, but also factors influencing it. The results of the studies reviewed showed a strong level of evidence to support the impairment of heart rate variability in the time domain. A similar evidence level was also found to support impairment in baroreceptor sensitivity and muscle sympathetic nerve activity. Furthermore, this review identified physical activity level, muscle function, and circadian rhythm as the major influencing factors (strong evidence) of autonomic function in subjects with COPD. However, no definite conclusion could be reached for factors such as dyspnea, anxiety, body composition, pulmonary function, age, breathing frequency, ventilatory effort, quality of life, and disease severity due to limited, conflicting, or lack of existing evidence. The results of this review highlight relevant clinical messages for clinicians and other health-care providers regarding the role autonomic function can play as an important physiological marker for prognostication and stratification. Hence, autonomic function outcomes should be identified and considered during management of patients with COPD. Moreover, this review can serve as basis for future research aimed at assessing the interventions for autonomic function abnormalities in these patients. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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