Identification of exercise-induced ischemia using QRS slopes.

In this work we studied a computer-aided approach using QRS slopes as unconventional ECG features to identify the exercise-induced ischemia during exercise stress testing and demonstrated that the performance is comparable to the experts' manual analysis using standard criteria involving ST-segment...

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Publicado en:Journal of Electrocardiology Vol. 49; no. 1; pp. 55 - 60
Autores principales: Firoozabadi, Reza, Gregg, Richard E., Babaeizadeh, Saeed
Formato: research Journal Article
Publicado: W B Saunders Jan/Feb2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan/Feb2016
      vid: 49
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      pub: W B Saunders
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        atl: Identification of exercise-induced ischemia using QRS slopes.
      aug:
        au:
          Firoozabadi, Reza
          Gregg, Richard E.
          Babaeizadeh, Saeed
        affil: Advanced Algorithm Research Center, Philips Healthcare, Andover, MA, USA
      sug:
        subj:
          Reproducibility of Results Methods
          Algorithms Methods
          Ischemia
          Myocardial Ischemia Diagnosis
          Exercise Test Methods
          Information Science
          Myocardial Ischemia
          Electrocardiography Methods
          Sensitivity and Specificity
          Electrocardiography
          Information Science Methods
          Ischemia Diagnosis
          Diagnosis, Computer Assisted
          Sensitivity and Specificity Methods
          Diagnosis, Computer Assisted Methods
          Exercise Test
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Human
      ab: In this work we studied a computer-aided approach using QRS slopes as unconventional ECG features to identify the exercise-induced ischemia during exercise stress testing and demonstrated that the performance is comparable to the experts' manual analysis using standard criteria involving ST-segment depression. We evaluated the performance of our algorithm using a database including 927 patients undergoing exercise stress tests and simultaneously collecting the ECG recordings and SPECT results. High resolution 12-lead ECG recordings were collected continuously throughout the rest, exercise, and recovery phases. Patients in the database were classified into three categories of moderate/severe ischemia, mild ischemia, and normal according to the differences in sum of the individual segment scores for the rest and stress SPECT images. Philips DXL 16-lead diagnostic algorithm was run on all 10-s segments of 12-lead ECG recordings for each patient to acquire the representative beats, ECG fiducial points from the representative beats, and other ECG parameters. The QRS slopes were extracted for each lead from the averaged representative beats and the leads with highest classification power were selected. We employed linear discriminant analysis and measured the performance using 10-fold cross-validation. Comparable performance of this method to the conventional ST-segment analysis exhibits the classification power of QRS slopes as unconventional ECG parameters contributing to improved identification of exercise-induced ischemia.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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