A Comparative Study Between Smartphone-Based Microscopy and Conventional Light Microscopy in 1021 Dermatopathology Specimens.

Context.--The incorporation of high-resolution cameras into smartphones has allowed for a variety of medical applications including the use of lens attachments that provide telescopic, macroscopic, and dermatoscopic data, but the feasibility and performance characteristics of such a platform for use...

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Publicado en:Archives of Pathology & Laboratory Medicine Vol. 140; no. 1; pp. 86 - 91
Autores principales: Jahan-Tigh, Richard R., Chinn, Garrett M., Rapini, Ronald P.
Formato: pictorial research tables/charts Journal Article
Publicado: College of American Pathologists Jan2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2016
      vid: 140
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      pub: College of American Pathologists
      place: Northfield, Illinois
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        atl: A Comparative Study Between Smartphone-Based Microscopy and Conventional Light Microscopy in 1021 Dermatopathology Specimens.
      aug:
        au:
          Jahan-Tigh, Richard R.
          Chinn, Garrett M.
          Rapini, Ronald P.
        affil: Department of Dermatology and Pathology, University of Texas Houston Health Science Center, Houston
      sug:
        subj:
          Microscopy
          Smartphone
          Dermatology
          Pathology, Clinical
          Melanoma Diagnosis
          Skin Neoplasms Diagnosis
          Carcinoma, Basal Cell Diagnosis
          Carcinoma, Squamous Cell Diagnosis
          Equipment Design
          Comparative Studies
          Prospective Studies
          Sensitivity and Specificity
          Descriptive Statistics
          Predictive Value of Tests
      ab: Context.--The incorporation of high-resolution cameras into smartphones has allowed for a variety of medical applications including the use of lens attachments that provide telescopic, macroscopic, and dermatoscopic data, but the feasibility and performance characteristics of such a platform for use in dermatopathology have not been described. Objective.--To determine the diagnostic performance of a smartphone microscope compared to traditional light microscopy in dermatopathology specimens. Design.--A simple smartphone microscope constructed with a 3-mm ball lens was used to prospectively evaluate 1021 consecutive dermatopathology cases in a blinded fashion. Referred, consecutive specimens from the community were evaluated at a single university hospital. The performance characteristics of the smartphone platform were calculated by using conventional light microscopy as the gold standard. The sensitivity and specificity for the diagnosis of melanoma, nonmelanoma skin cancers, and other miscellaneous conditions by the phone microscopy platform, as compared with traditional light microscopy, were calculated. Results.--For basal cell carcinoma (n = 136), the sensitivity and specificity of smartphone microscopy were 95.6% and 98.1 %, respectively. The sensitivity and specificity for squamous cell carcinoma (n = 94) were 89.4% and 97.3%, respectively. The lowest sensitivity was found in melanoma (n = 15) at 60%, although the specificity was high at 99.1%. The accuracy of diagnosis of inflammatory conditions and other neoplasms was variable. Conclusions.--Mobile phone-based microscopy has excellent performance characteristics for the inexpensive diagnosis of nonmelanoma skin cancers in a setting where a traditional microscope is not available.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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