Comparison of Transcutaneous and Capillary Measurement of ... in Hypercapnic Subjects.

BACKGROUND: Measurement of ... is vital in determining effective alveolar ventilation. However, obtaining capillary ... by a skin prick of the earlobe is painful, and nocturnal measurements disturb sleep. End-expiratory measurement of ... is also well established, but there is a low precision in pre...

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Detalles Bibliográficos
Publicado en:Respiratory Care Vol. 61; no. 1; pp. 98 - 106
Autores principales: Stieglitz, Sven, Matthes, Sandhya, Priegnitz, Christina, Hagmeyer, Lars, Randerath, Winfried
Formato: research tracings Journal Article
Publicado: Mary Ann Liebert, Inc. Jan2016
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Mary Ann Liebert, Inc.
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        10.4187/respcare.03917
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        atl: Comparison of Transcutaneous and Capillary Measurement of ... in Hypercapnic Subjects.
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        au:
          Stieglitz, Sven
          Matthes, Sandhya
          Priegnitz, Christina
          Hagmeyer, Lars
          Randerath, Winfried
        affil: Department of Pneumology and Cardiology, Petrus Hospital Wuppertal, Academic Teaching Hospital of the University of Duesseldorf, Wuppertal, Germany
      sug:
        subj:
          Blood Gas Monitoring, Transcutaneous
          Carbon Dioxide
          Hypercapnia
          Capillaries
          Prospective Studies
          Heart Rate
          Ear
          Hypoventilation
          Human
          Male
          Female
          Adult
          Middle Age
          Descriptive Statistics
          Data Analysis Software
          Scoliosis
          Pulmonary Disease, Chronic Obstructive
          Obesity
          Arterial Pressure
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: BACKGROUND: Measurement of ... is vital in determining effective alveolar ventilation. However, obtaining capillary ... by a skin prick of the earlobe is painful, and nocturnal measurements disturb sleep. End-expiratory measurement of ... is also well established, but there is a low precision in predicting arterial or capillary CO2. The purpose of the study was to evaluate nocturnal measurement of noninvasive, transcutaneous ... (...) measurement in hypercapnic subjects. METHODS: In this prospective study, 31 subjects with chronic hypercapnic failure--in a stable phase of the underlying disease--and a control group of 12 healthy volunteers were included. Transcutaneous measurements were taken by the Tosca sensor (Radiometer, Copenhagen, Denmark) over a period of at least 6 h during the night. A capillary blood gas was measured at midnight and 4:00 am. RESULTS: The mean nocturnal capillary ... (...) of subjects was 50.6 ± 10.2 mm Hg. In the 31 subjects with known hypercapnic respiratory failure, the correlation between ..., and ... at midnight was 0.86 and at 4:00 am r = 0.80. The bias of the hypercapnic subjects was d = + 4.5 with a limit(s) of agreement of 2 SD = 13.0. The process of blood sampling caused no significant change in .... CONCLUSIONS: Our study evaluated transcutaneous capnography as a continuous nocturnal measurement in hypercapnic subjects. We found a good agreement between the methods. Because CO2 is not constant in patients with respiratory failure, but instead fluctuates, we would recommend the continuous transcutaneous measurement of ... as our method of choice in the diagnosis of nocturnal hypercapnia.
      pubtype: Academic Journal
      doctype:
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        tracings
        Journal Article
      ougenre: Article
    language: English
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