Characterization of the disposition of fostamatinib in Japanese subjects including pharmacokinetic assessment in dry blood spots: results from two phase I clinical studies.

Purpose: The aims of the present study were to characterize the pharmacokinetics of fostamatinib in two phase I studies in healthy Japanese subjects after single- and multiple-dose administration, and to evaluate the utility of dried blood spot (DBS) sampling. Methods: In study A, 40 Japanese and 16...

Full description

Bibliographic Details
Published in:European Journal of Clinical Pharmacology Vol. 72; no. 1; pp. 61 - 72
Main Authors: Martin, Paul, Cheung, S., Yen, Mark, Han, David, Gillen, Michael
Format: research tables/charts randomized controlled trial Journal Article
Published: Springer Nature Jan2016
Online Access:View this record in EBSCOhost