Effectiveness of an individualized program of muscular strength and endurance with aerobic training for improving germ cell cancer-related fatigue in men undergoing chemotherapy: EFICATEST study protocol for a randomized controlled trial.
Background: Patients with testicular germ cell cancer (GCC) have a high cure rate; however, cancer-related fatigue is the most common complication among patients with GCC undergoing treatment with chemotherapy. Although exercise is widely recommended, information about the physio-pathological effect...
| Publicado en: | Trials Vol. 17; pp. 1 - 6 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
BioMed Central
1/5/2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112134194&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 112134194 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17456215 38OC jtl: Trials issn: 17456215 maglogo: N pubinfo: dt: 1/5/2016 vid: 17 pid: 24147 pub: BioMed Central artinfo: ui: 112134194 112134194 NLM26732120 112134194 10.1186/s13063-015-1143-x NLM26732120 PMC4702371 112134194 ppf: 1 ppct: 5 formats: tig: atl: Effectiveness of an individualized program of muscular strength and endurance with aerobic training for improving germ cell cancer-related fatigue in men undergoing chemotherapy: EFICATEST study protocol for a randomized controlled trial. aug: au: Cuesta-Vargas, Antonio Ignacio Carabantes, Francisco Caracuel, Zaira Conejo, Inmaculada Alba, Emilio affil: Department of Physiotherapy, Faculty of Health Sciences, Instituto de Investigacion de Biomedicina de Malaga (IBIMA), Universidad de Malaga, Málaga, Spain sug: subj: Neoplasms, Germ Cell and Embryonal Drug Therapy Protocols Muscle Strength Fatigue Therapy Testicular Neoplasms Drug Therapy Physical Endurance Adult Biochemistry Middle Age Adolescence Testicular Neoplasms Physiopathology Data Analysis, Statistical Male Exercise Neoplasms, Germ Cell and Embryonal Physiopathology Validation Studies Comparative Studies Evaluation Research Multicenter Studies Human Randomized Controlled Trials Adult: 19-44 years Middle Aged: 45-64 years Adolescent: 13-18 years Male ab: Background: Patients with testicular germ cell cancer (GCC) have a high cure rate; however, cancer-related fatigue is the most common complication among patients with GCC undergoing treatment with chemotherapy. Although exercise is widely recommended, information about the physio-pathological effects of cancer therapy on skeletal muscle is very limited. Our aim is to evaluate the effects of an individualized program of muscular strength and endurance with aerobic training on cancer-related fatigue.Methods/design: The present study is a randomized controlled trial comparing an individualized program of muscular strength and endurance with aerobic training compared to a control group. We will conduct this trial in patients undergoing chemotherapy, recruited by the Department of Oncology of Virgen de la Victoria Hospital (Málaga). Patients will be included and evaluated before the first cycle of chemotherapy and assigned randomly to the experimental or control group. Cancer-related fatigue, physical condition and biological samples will be measured at the beginning and at the end of an 8-week intervention by the same evaluator, who will be unaware of the allocation of participants to each group. Furthermore, there will be monitoring for 6 months (24 weeks) after training for all outcome variables.Discussion: This study hopes to offer patients with GCC an individualized exercise program with aerobic training for cancer-related fatigue. Such a scheme, if beneficial, could be implemented successfully within public health.Trial Registration: ClinicalTrials.gov Identifier: NCT02433197 . Date of registration: 13 April 2015. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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