Different forms of iron accumulation in the liver on MRI.

Magnetic resonance imaging (MRI) is a well-established imaging modality to evaluate increased iron deposition in the liver. Both standard liver imaging series with in-phase and out-of-phase T1-weighted sequences for visual detection, as well as advanced T2- and T2*-weighted measurements may be used...

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Publicado en:Diagnostic & Interventional Radiology Vol. 22; no. 1; pp. 22 - 29
Autores principales: İdilman, İlkay S., Akata, Deniz, Özmen, Mustafa Nasuh, Karçaaltıncaba, Muþturay, Karçaaltıncaba, Muşturay
Formato: research Journal Article
Publicado: Galenos Yayinevi Tic. LTD. STI Jan2016
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Different forms of iron accumulation in the liver on MRI.
      aug:
        au:
          İdilman, İlkay S.
          Akata, Deniz
          Özmen, Mustafa Nasuh
          Karçaaltıncaba, Muþturay
          Karçaaltıncaba, Muşturay
        affil: Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey
      sug:
        subj:
          Magnetic Resonance Imaging Methods
          Iron Overload
          Image Processing, Computer Assisted Methods
          Imaging, Three-Dimensional
          Fatty Liver Pathology
          Iron Overload Metabolism
          Liver Metabolism
          Fatty Liver
          Contrast Media
          Fatty Liver Metabolism
          Liver Pathology
          Liver
          Iron Overload Pathology
          Human
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
      ab: Magnetic resonance imaging (MRI) is a well-established imaging modality to evaluate increased iron deposition in the liver. Both standard liver imaging series with in-phase and out-of-phase T1-weighted sequences for visual detection, as well as advanced T2- and T2*-weighted measurements may be used for mapping the iron concentration. In this article, we describe different forms of liver iron accumulation (diffuse, heterogeneous, multinodular, focal, segmental, intralesional, periportal, and lobar) and hepatic iron sparing (focal, geographic and nodular). Focal iron sparing is characterized by hypointense areas on R2* map and hyperintense areas on T2* map. We also illustrate MRI findings of simultaneous hepatic iron and fat accumulation. Coexistence of iron (siderosis) and fat (steatosis) can make interpretation of in- and out-of-phase T1-weighted images difficult; calculation of proton density fat fraction and R2* maps can characterize abnormal signal changes observed on in- and out-of-phase images. Knowledge of different forms of hepatic iron overload and iron sparing and evaluation of T2* and R2* maps would allow correct diagnosis of iron-associated liver disorders.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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