Proton magnetic resonance spectroscopy in oncology: the fingerprints of cancer?

Abnormal metabolism is a key tumor hallmark. Proton magnetic resonance spectroscopy (1H-MRS) allows measurement of metabolite concentration that can be utilized to characterize tumor metabolic changes. 1H-MRS measurements of specific metabolites have been implemented in the clinic. This article perf...

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Bibliographic Details
Published in:	Diagnostic & Interventional Radiology Vol. 22; no. 1; pp. 75 - 90
Main Authors:	García-Figueiras, Roberto, Baleato-González, Sandra, Padhani, Anwar R., Oleaga, Laura, Vilanova, Joan C., Luna, Antonio, Gómez, Juan Carlos Cobas, Cobas Gómez, Juan Carlos
Format:	diagnostic images pictorial review tables/charts Journal Article
Published:	Galenos Yayinevi Tic. LTD. STI Jan2016
Online Access:	View this record in EBSCOhost

Description
Summary:	Abnormal metabolism is a key tumor hallmark. Proton magnetic resonance spectroscopy (1H-MRS) allows measurement of metabolite concentration that can be utilized to characterize tumor metabolic changes. 1H-MRS measurements of specific metabolites have been implemented in the clinic. This article performs a systematic review of image acquisition and interpretation of 1H-MRS for cancer evaluation, evaluates its strengths and limitations, and correlates metabolite peaks at 1H-MRS with diagnostic and prognostic parameters of cancer in different tumor types.