The Autism Diagnostic Observation Schedule, Module 4: Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (n = 93).

This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in J Autism Dev Disord 44(8):1996-2012, ) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 46; no. 1; pp. 21 - 31
Autores principales: Bildt, Annelies, Sytema, Sjoerd, Meffert, Harma, Bastiaansen, Jojanneke
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jan2016
Acceso en línea:Ver este registro en EBSCOhost
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      place: New York, New York
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        atl: The Autism Diagnostic Observation Schedule, Module 4: Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (n = 93).
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        au:
          Bildt, Annelies
          Sytema, Sjoerd
          Meffert, Harma
          Bastiaansen, Jojanneke
        affil: Interdisciplinary Center for Psychopathology and Emotion Regulation (ICPE), Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen The Netherlands
      sug:
        subj:
          Instrument Validation
          Autism Spectrum Disorder Diagnosis
          Algorithms
          Diagnosis, Differential
          Human
          Netherlands
          Descriptive Statistics
          Male
          Clinical Assessment Tools
          Schizophrenia Diagnosis
          Sensitivity and Specificity
          Adult
          Adolescence
          Middle Age
          Aged
          Data Analysis Software
          Multivariate Analysis of Variance
          Post Hoc Analysis
          McNemar's Test
          ROC Curve
          Logistic Regression
          Odds Ratio
          Confidence Intervals
          Chi Square Test
          Reference Values
          Funding Source
          Adult: 19-44 years
          Adolescent: 13-18 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
      ab: This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in J Autism Dev Disord 44(8):1996-2012, ) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the revised algorithm ASD cut-off resembled the original algorithm ASD cut-off: highly specific for psychopathy and controls, lower sensitivity than Hus and Lord (; i.e. ASD .61, AD .53). The revised algorithm AD cut-off improved sensitivity over the original algorithm. Discriminating ASD from schizophrenia was still challenging, but the better-balanced sensitivity (.53) and specificity (.78) of the revised algorithm AD cut-off may aide clinicians' differential diagnosis. Findings support using the revised algorithm, being conceptually conform the other modules, thus improving comparability across the lifespan.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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