Comparison of cone-beam CT-guided and CT fluoroscopy-guided transthoracic needle biopsy of lung nodules.
Purpose: To compare the diagnostic performance of cone-beam CT (CBCT)-guided and CT fluoroscopy (fluoro-CT)-guided technique for transthoracic needle biopsy (TNB) of lung nodules.Methods: The hospital records of 319 consecutive patients undergoing 324 TNBs of lung nodules in a single radiology unit...
| Publicado en: | European Radiology Vol. 26; no. 2; pp. 381 - 390 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Feb2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112262156&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 112262156 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Feb2016 vid: 26 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 112262156 112262156 NLM26045345 112262156 10.1007/s00330-015-3861-6 NLM26045345 112262156 ppf: 381 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Comparison of cone-beam CT-guided and CT fluoroscopy-guided transthoracic needle biopsy of lung nodules. aug: au: Rotolo, Nicola Floridi, Chiara Imperatori, Andrea Fontana, Federico Ierardi, Anna Mangini, Monica Arlant, Veronica De Marchi, Giuseppe Novario, Raffaele Dominioni, Lorenzo Fugazzola, Carlo Carrafiello, Gianpaolo Ierardi, Anna Maria affil: Center for Thoracic Surgery, Insubria University, Viale Borri 57 21100 Varese Italy sug: subj: Lung Neoplasms Radiography Radiography, Interventional Methods Radiation Dosage Male Aged Sensitivity and Specificity Biopsy, Needle Methods Fluoroscopy Methods Adult Female Tomography, X-Ray Computed Methods Lung Neoplasms Pathology Biopsy Methods Retrospective Design Middle Age Human Validation Studies Comparative Studies Evaluation Research Multicenter Studies Aged: 65+ years Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Purpose: To compare the diagnostic performance of cone-beam CT (CBCT)-guided and CT fluoroscopy (fluoro-CT)-guided technique for transthoracic needle biopsy (TNB) of lung nodules.Methods: The hospital records of 319 consecutive patients undergoing 324 TNBs of lung nodules in a single radiology unit in 2009-2013 were retrospectively evaluated. The newly introduced CBCT technology was used to biopsy 123 nodules; 201 nodules were biopsied by conventional fluoro-CT-guided technique. We assessed the performance of the two biopsy systems for diagnosis of malignancy and the radiation exposure.Results: Nodules biopsied by CBCT-guided and by fluoro-CT-guided technique had similar characteristics: size, 20 ± 6.5 mm (mean ± standard deviation) vs. 20 ± 6.8 mm (p = 0.845); depth from pleura, 15 ± 15 mm vs. 15 ± 16 mm (p = 0.595); malignant, 60% vs. 66% (p = 0.378). After a learning period, the newly introduced CBCT-guided biopsy system and the conventional fluoro-CT-guided system showed similar sensitivity (95% and 92%), specificity (100% and 100%), accuracy for diagnosis of malignancy (96% and 94%), and delivered non-significantly different median effective doses [11.1 mSv (95 % CI 8.9-16.0) vs. 14.5 mSv (95% CI 9.5-18.1); p = 0.330].Conclusion: The CBCT-guided and fluoro-CT-guided systems for lung nodule biopsy are similar in terms of diagnostic performance and effective dose, and may be alternatively used to optimize the available technological resources.Key Points: • CBCT-guided and fluoro-CT-guided lung nodule biopsy provided high and similar diagnostic accuracy. • Effective dose from CBCT-guided and fluoro-CT-guided lung nodule biopsy was similar. • To optimize resources, CBCT-guided lung nodule biopsy may be an alternative to fluoro-CT-guided. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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