Effect of acute intermittent hypoxia treatment on ventilatory load compensation and magnitude estimation of inspiratory resistive loads in an individual with chronic incomplete cervical spinal cord injury.

Context: Spinal cord injury (SCI) causes disruption of the efferent input to and afferent input from respiratory muscles, which impairs respiratory motor and sensory functions, respectively. This disturbs the injured individual's ability to respond to ventilatory loads and may alter the respiratory...

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Publicado en:Journal of Spinal Cord Medicine Vol. 39; no. 1; pp. 103 - 111
Autores principales: Jaiswal, Poonam B., Tester, Nicole J., Davenport, Paul W.
Formato: case study research Journal Article
Publicado: Taylor & Francis Ltd Jan2016
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Journal of Spinal Cord Medicine
      issn: 10790268
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      dt: Jan2016
      vid: 39
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        112378728
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        112378728
        10.1179/2045772314Y.0000000277
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        atl: Effect of acute intermittent hypoxia treatment on ventilatory load compensation and magnitude estimation of inspiratory resistive loads in an individual with chronic incomplete cervical spinal cord injury.
      aug:
        au:
          Jaiswal, Poonam B.
          Tester, Nicole J.
          Davenport, Paul W.
        affil: Department of Physiological Sciences, University of Florida, Gainesville, FL, USA
      sug:
        subj:
          Cervical Vertebrae Injuries
          Spinal Cord Injuries Rehabilitation
          Respiratory Therapy Methods
          Work of Breathing
          Carbon Dioxide Therapeutic Use
          Female
          Human
          Middle Age
          Recovery
          Scales
          Funding Source
          Middle Aged: 45-64 years
          Female
      ab: Context: Spinal cord injury (SCI) causes disruption of the efferent input to and afferent input from respiratory muscles, which impairs respiratory motor and sensory functions, respectively. This disturbs the injured individual's ability to respond to ventilatory loads and may alter the respiratory perceptual sensitivity of applied loads. Acute intermittent hypoxia with elevated CO(2) (AIH treatment) has been shown to induce ventilatory long-term facilitation in individuals with chronic SCI. This study evaluated the effect of ten days of AIH treatment on ventilatory load compensation and respiratory perceptual sensitivity to inspiratory resistive loads (IRL), in an individual with chronic, incomplete cervical SCI.Methods: Case report and literature review.Findings: We report a case of a 55-year-old female with a C4 chronic, incomplete SCI (American Spinal Injury Association Impairment Scale D). The subject underwent evaluation at four time-points: Baseline, Post Sham, AIH Day 1 and AIH Day 10. Significant improvements in airflow generated in response to applied IRL were found after AIH treatment compared to Baseline. There were no significant changes in the respiratory perceptual sensitivity to applied IRL after AIH treatment.Clinical Relevance: Rehabilitative interventions after SCI demand restoration of the respiratory motor function. However, they must also ensure that the respiratory perceptual sensitivity of the injured individual does not hinder their capability to compensate to ventilatory challenges.
      pubtype: Academic Journal
      doctype:
        case study
        research
        Journal Article
      ougenre: Article
    language: English
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