Subjects At-Risk for Genetic Diseases in Portugal: Illness Representations.

This study investigates illness representations of subjects at-risk for 3 autosomal dominant late-onset disorders: Familial Amyloid Polyneuropathy (FAP) TTR V30M, Huntington's disease (HD) and Machado-Joseph disease (MJD), comparing them with the illness representations of subjects at-risk for Hemoc...

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Publicado en:Journal of Genetic Counseling Vol. 25; no. 1; pp. 79 - 90
Autores principales: Leite, Ângela, Sequeiros, Jorge, Dinis, Maria, Paúl, Constança
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Feb2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2016
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1007/s10897-015-9846-4
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        atl: Subjects At-Risk for Genetic Diseases in Portugal: Illness Representations.
      aug:
        au:
          Leite, Ângela
          Sequeiros, Jorge
          Dinis, Maria
          Paúl, Constança
        affil: Faculty of Science and Technology (FCT-UFP), University of Fernando Pessoa, Porto Portugal
      sug:
        subj:
          Hereditary Diseases Risk Factors
          Disease Attributes
          Male
          Female
          Human
          Amyloid Neuropathies, Familial Risk Factors
          Portugal
          Huntington's Disease Risk Factors
          Cerebellar Diseases Risk Factors
          Hemochromatosis Risk Factors
          Genetic Counseling
          Semi-Structured Interview
          Heterozygote
          Male
          Female
      ab: This study investigates illness representations of subjects at-risk for 3 autosomal dominant late-onset disorders: Familial Amyloid Polyneuropathy (FAP) TTR V30M, Huntington's disease (HD) and Machado-Joseph disease (MJD), comparing them with the illness representations of subjects at-risk for Hemochromatosis (HH). The present study included a clinical group that consisted of 213 subjects at genetic risk (FAP, HD and MJD), comprising 174 subjects at-risk for FAP, 34 subjects at-risk for HD and only 5 subjects at-risk for MJD; and the control group consisting of 31 subjects at genetic risk for HH. All subjects at-risk were undergoing the process of genetic counseling to learn their genetic status (carrier or non-carrier). Subjects were assessed through a semi-structured single interview, in order to obtain sociodemographic data and the answer to an open-ended question relating to the illness representation issue: 'What does this illness mean to you?/ What is this disease to you?' It was in the subjects' metaphors that subjects best expressed what they felt regarding the disease and the situation of being at-risk for this disease. Family is their mirror and their source of learning and, therefore, it is inevitable that family is related to the meaning of the disease itself.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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