Evaluation of diagnostic accuracy in CT perfusion analysis in moyamoya disease.
Purpose: The purpose of the present study was to determine optimal threshold of vascular pixel elimination (VPE) for CT perfusion (CTP) and to assess diagnostic accuracy of CTP by comparing with xenon enhanced CT (XeCT) in moyamoya disease.Materials and Methods: Twenty-three patients underwent XeCT...
| Publicado en: | Japanese Journal of Radiology Vol. 34; no. 1; pp. 28 - 35 |
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| Autores principales: | , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jan2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112464338&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 112464338 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18671071 AUCM jtl: Japanese Journal of Radiology issn: 18671071 maglogo: N pubinfo: dt: Jan2016 vid: 34 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 112464338 112464338 NLM26553201 112464338 10.1007/s11604-015-0497-z NLM26553201 112464338 ppf: 28 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Evaluation of diagnostic accuracy in CT perfusion analysis in moyamoya disease. aug: au: Ohno, Takashi Kudo, Kohsuke Zaharchuk, Greg Fujima, Noriyuki Shirato, Hiroki affil: Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Sapporo Japan sug: subj: Carotid Arteries Radiography Tomography, X-Ray Computed Moyamoya Disease Radiography Cerebral Arteries Radiography Blood Flow Velocity Adult Aged Middle Age Gases Contrast Media Image Processing, Computer Assisted Radiographic Image Enhancement Male Female Reproducibility of Results Cerebrovascular Circulation Human Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Male Female ab: Purpose: The purpose of the present study was to determine optimal threshold of vascular pixel elimination (VPE) for CT perfusion (CTP) and to assess diagnostic accuracy of CTP by comparing with xenon enhanced CT (XeCT) in moyamoya disease.Materials and Methods: Twenty-three patients underwent XeCT and CTP. Cerebral blood flow (CBF) images were generated for XeCT and CTP using nine types of software. Region of interest (ROI) measurement was performed on XeCT-CBF and CTP-CBF. Linear regression analysis was performed between XeCT-CBF and CTP-CBF in all software, without and with VPE. The Pearson correlation coefficient was calculated, and an optimal threshold was determined based on maximum correlation coefficients. Correlation coefficients at various VPE thresholds including data of no-VPE were compared with each other. The maximum correlation coefficient at the optimal threshold was also compared.Results: Optimal thresholds varied among software types (0.8-2.2 and 7-14 ml/100 g in relative and absolute VPE, respectively). There were significant differences between correlation coefficients at a range of VPE thresholds compared to no-VPE in most software types. There were significant differences in maximum correlation coefficient at optimal threshold among various software types.Conclusion: Optimal threshold of VPE for CTP could be determined and diagnostic accuracy of CTP varied among software types in moyamoya disease. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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