Multicenter study of quantitative computed tomography analysis using a computer-aided three-dimensional system in patients with idiopathic pulmonary fibrosis.

Purpose: To evaluate the feasibility of automated quantitative analysis with a three-dimensional (3D) computer-aided system (i.e., Gaussian histogram normalized correlation, GHNC) of computed tomography (CT) images from different scanners.Materials and Methods: Each institution's review board approv...

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Publicado en:Japanese Journal of Radiology Vol. 34; no. 1; pp. 16 - 28
Autores principales: Iwasawa, Tae, Kanauchi, Tetsu, Hoshi, Toshiko, Ogura, Takashi, Baba, Tomohisa, Gotoh, Toshiyuki, Oba, Mari, Oba, Mari S
Formato: research Journal Article
Publicado: Springer Nature Jan2016
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Japanese Journal of Radiology
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      dt: Jan2016
      vid: 34
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11604-015-0496-0
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        atl: Multicenter study of quantitative computed tomography analysis using a computer-aided three-dimensional system in patients with idiopathic pulmonary fibrosis.
      aug:
        au:
          Iwasawa, Tae
          Kanauchi, Tetsu
          Hoshi, Toshiko
          Ogura, Takashi
          Baba, Tomohisa
          Gotoh, Toshiyuki
          Oba, Mari
          Oba, Mari S
        affil: Department of Radiology, Kanagawa Cardiovascular and Respiratory Center, 6-16-1, Tomioka-higashi, Kanazawa-ku Yokohama 236-8651 Japan
      sug:
        subj:
          Idiopathic Pulmonary Fibrosis Radiography
          Tomography, X-Ray Computed Methods
          Imaging, Three-Dimensional Methods
          Lung Radiography
          Female
          Human
          Aged, 80 and Over
          Aged
          Middle Age
          Prospective Studies
          Male
          Pilot Studies
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Aged, 80 & over
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Purpose: To evaluate the feasibility of automated quantitative analysis with a three-dimensional (3D) computer-aided system (i.e., Gaussian histogram normalized correlation, GHNC) of computed tomography (CT) images from different scanners.Materials and Methods: Each institution's review board approved the research protocol. Informed patient consent was not required. The participants in this multicenter prospective study were 80 patients (65 men, 15 women) with idiopathic pulmonary fibrosis. Their mean age was 70.6 years. Computed tomography (CT) images were obtained by four different scanners set at different exposures. We measured the extent of fibrosis using GHNC, and used Pearson's correlation analysis, Bland-Altman plots, and kappa analysis to directly compare the GHNC results with manual scoring by radiologists. Multiple linear regression analysis was performed to determine the association between the CT data and forced vital capacity (FVC).Results: For each scanner, the extent of fibrosis as determined by GHNC was significantly correlated with the radiologists' score. In multivariate analysis, the extent of fibrosis as determined by GHNC was significantly correlated with FVC (p < 0.001). There was no significant difference between the results obtained using different CT scanners.Conclusion: Gaussian histogram normalized correlation was feasible, irrespective of the type of CT scanner used.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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