Non-invasive prediction of portal pressures using CT and MRI in chronic liver disease.
Purpose: To assess the diagnostic value of a fast scoring system based on non-invasive cross-sectional imaging to predict portal hypertension (PH) in patients with liver disease. Methods: In this retrospective study, we included patients who underwent contrast-enhanced CT or MRI within 3 months of h...
| Publicado en: | Abdominal Radiology Vol. 41; no. 1; pp. 42 - 50 |
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| Autores principales: | , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jan2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=112693118&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 112693118 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Jan2016 vid: 41 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 112693118 10.1007/s00261-015-0614-6 112693118 ppf: 42 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Non-invasive prediction of portal pressures using CT and MRI in chronic liver disease. aug: au: Kihira, Shingo Kagen, Alexander Vasudevan, Prasanna Jajamovich, Guido Schiano, Thomas Andrle, Anne-Fleur Babb, James Fischman, Aaron Taouli, Bachir affil: Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue New York 10029 USA sug: ab: Purpose: To assess the diagnostic value of a fast scoring system based on non-invasive cross-sectional imaging to predict portal hypertension (PH) in patients with liver disease. Methods: In this retrospective study, we included patients who underwent contrast-enhanced CT or MRI within 3 months of hepatic venous pressure gradient (HVPG) measurements. Two independent observers provided an imaging-based scoring system (max of 9): number of variceal sites, volume of ascites, and spleen size. ROC analysis was performed to predict the presence of PH (HVPG ≥ 5 mmHg) and clinically significant PH (HVPG ≥ 10 mmHg). Results: Our cohort consists of 143 patients with mean HVPG of 13.1 ± 2.0 mmHg. Mean PH scores from the two observers were 3.9 ± 2.7 and 3.2 ± 2.5. There was a significant correlation between PH score and HVPG ( r = 0.58, p < 0.001 for both observers) with high inter-observer agreement (kappa 0.71). AUCs of 0.78-0.76 and 0.83-0.81 were observed for diagnosing HVPG ≥ 5 mmHg and HVPG ≥ 10 mmHg, respectively, for observers 1 and 2. Conclusions: We have developed a fast PH imaging-based composite score, which could be used for non-invasive detection of clinically significant PH. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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