Abdominal fat volume estimation by stereology on CT: a comparison with manual planimetry.

Objectives: To deploy and evaluate a stereological point-counting technique on abdominal CT for the estimation of visceral (VAF) and subcutaneous abdominal fat (SAF) volumes.Methods: Stereological volume estimations based on point counting and systematic sampling were performed on images from 14 con...

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Publicado en:European Radiology Vol. 26; no. 3; pp. 706 - 714
Autores principales: Manios, G., Mazonakis, M., Voulgaris, C., Karantanas, A., Damilakis, J., Manios, G E
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Mar2016
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Abdominal fat volume estimation by stereology on CT: a comparison with manual planimetry.
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          Manios, G.
          Mazonakis, M.
          Voulgaris, C.
          Karantanas, A.
          Damilakis, J.
          Manios, G E
        affil: Department of Medical Physics, Faculty of Medicine, University of Crete, Heraklion Greece
      sug:
        subj:
          Reproducibility of Results
          Regression
          Abdominal Fat Radiography
          Abdomen
          Tomography, X-Ray Computed
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Male
          Middle Age
          Aged
          Female
          Adult
          Human
          Middle Aged: 45-64 years
          Aged: 65+ years
          Adult: 19-44 years
          Male
          Female
      ab: Objectives: To deploy and evaluate a stereological point-counting technique on abdominal CT for the estimation of visceral (VAF) and subcutaneous abdominal fat (SAF) volumes.Methods: Stereological volume estimations based on point counting and systematic sampling were performed on images from 14 consecutive patients who had undergone abdominal CT. For the optimization of the method, five sampling intensities in combination with 100 and 200 points were tested. The optimum stereological measurements were compared with VAF and SAF volumes derived by the standard technique of manual planimetry on the same scans.Results: Optimization analysis showed that the selection of 200 points along with the sampling intensity 1/8 provided efficient volume estimations in less than 4 min for VAF and SAF together. The optimized stereology showed strong correlation with planimetry (VAF: r = 0.98; SAF: r = 0.98). No statistical differences were found between the two methods (VAF: P = 0.81; SAF: P = 0.83). The 95% limits of agreement were also acceptable (VAF: -16.5%, 16.1%; SAF: -10.8%, 10.7%) and the repeatability of stereology was good (VAF: CV = 4.5%, SAF: CV = 3.2%).Conclusions: Stereology may be successfully applied to CT images for the efficient estimation of abdominal fat volume and may constitute a good alternative to the conventional planimetric technique.Key Points: Abdominal obesity is associated with increased risk of disease and mortality. Stereology may quantify visceral and subcutaneous abdominal fat accurately and consistently. The application of stereology to estimating abdominal volume fat reduces processing time. Stereology is an efficient alternative method for estimating abdominal fat volume.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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