Application of Computer-Aided Diagnosis to the Sonographic Evaluation of Cervical Lymph Nodes.

We initiated an observer study to evaluate a computerized system developed in our previous study for automatic extraction of 10 features and estimation of the malignancy probability of cervical nodes in sonograms. In the present study, five expert radiologists and five resident radiologists interpre...

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Publicado en:Ultrasonic Imaging Vol. 38; no. 2; pp. 159 - 172
Autores principales: Zhang, Junhua, Wang, Yuanyuan, Yu, Bo, Shi, Xinling, Zhang, Yufeng
Formato: research Journal Article
Publicado: Sage Publications Inc. Mar2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2016
      vid: 38
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        10.1177/0161734615589080
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        112942084
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        atl: Application of Computer-Aided Diagnosis to the Sonographic Evaluation of Cervical Lymph Nodes.
      aug:
        au:
          Zhang, Junhua
          Wang, Yuanyuan
          Yu, Bo
          Shi, Xinling
          Zhang, Yufeng
        affil: Department of Electronic Engineering, Yunnan University, Kunming, People's Republic of China
      sug:
        subj:
          Ultrasonography
          Lymphatic Diseases
          Lymph Nodes
          Diagnosis, Computer Assisted Methods
          Sensitivity and Specificity
          Observer Bias
          Biopsy
          Neck
          Human
          Neoplasm Metastasis
          Lymphatic Diseases Pathology
          ROC Curve
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
      ab: We initiated an observer study to evaluate a computerized system developed in our previous study for automatic extraction of 10 features and estimation of the malignancy probability of cervical nodes in sonograms. In the present study, five expert radiologists and five resident radiologists interpreted the sonograms of 178 nodes. The malignancy rating and patient management recommendation (biopsy or follow-up) were made without and then with the computer aid. Under these two reading conditions, the performances of radiologists and agreement among a group of radiologists were evaluated by using the receiver operating characteristic (ROC) analysis and the κ statistic, respectively. With the computer aid, the performances of radiologists improved significantly, as indicated by the increase in the area under the ROC curve (Az) from 0.843 to 0.896 (p = 0.031) and from 0.705 to 0.822 (p < 0.001), for the expert and resident groups, respectively. Agreement among all 10 radiologists improved from slight to moderate as indicated by an increase in the κ value from 0.195 to 0.421 (p < 0.001). The average performance of residents with aid (Az = 0.822) was close to that of experts without aid (Az = 0.843). Results indicate that computer-aided diagnosis is useful to improve radiologist performance (especially that of inexperienced radiologists) in the ultrasonographic evaluation of cervical nodes and to reduce variability among radiologists.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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