Harmonization in laboratory medicine: Requests, samples, measurements and reports.
In laboratory medicine, the terms “standardization” and “harmonization” are frequently used interchangeably as the final goal is the same: the equivalence of measurement results among different routine measurement procedures over time and space according to defined analytical and clinical quality sp...
| Publicado en: | Critical Reviews in Clinical Laboratory Sciences Vol. 53; no. 3; pp. 184 - 197 |
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| Autor principal: | |
| Formato: | review Journal Article |
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Taylor & Francis Ltd
Jun2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113081979&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 113081979 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10408363 1AV jtl: Critical Reviews in Clinical Laboratory Sciences issn: 10408363 maglogo: Y pubinfo: dt: Jun2016 vid: 53 iid: 3 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 113081979 113081979 113081979 10.3109/10408363.2015.1116851 113081979 ppf: 184 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Harmonization in laboratory medicine: Requests, samples, measurements and reports. aug: au: Plebani, Mario affil: Department of Laboratory Medicine, University-Hospital, Padova, Italy sug: subj: Laboratories Medicine Reliability Patient Safety Patient Care World Health ab: In laboratory medicine, the terms “standardization” and “harmonization” are frequently used interchangeably as the final goal is the same: the equivalence of measurement results among different routine measurement procedures over time and space according to defined analytical and clinical quality specifications. However, the terms define two distinct, albeit closely linked, concepts based on traceability principles. The word “standardization” is used when results for a measurement are equivalent and traceable to the International System of Units (SI) through a high-order primary reference material and/or a reference measurement procedure (RMP). “Harmonization” is generally used when results are equivalent, but neither a high-order primary reference material nor a reference measurement procedure is available. Harmonization is a fundamental aspect of quality in laboratory medicine as its ultimate goal is to improve patient outcomes through the provision of accurate and actionable laboratory information. Patients, clinicians and other healthcare professionals assume that clinical laboratory tests performed by different laboratories at different times on the same sample and specimen can be compared, and that results can be reliably and consistently interpreted. Unfortunately, this is not necessarily the case, because many laboratory test results are still highly variable and poorly standardized and harmonized. Although the initial focus was mainly on harmonizing and standardizing analytical processes and methods, the scope of harmonization now also includes all other aspects of the total testing process (TTP), such as terminology and units, report formats, reference intervals and decision limits as well as tests and test profiles, requests and criteria for interpretation. Several projects and initiatives aiming to improve standardization and harmonization in the testing process are now underway. Laboratory professionals should therefore step up their efforts to provide interchangeable and comparable laboratory information in order to ultimately assure better diagnosis and treatment in patient care. pubtype: Academic Journal doctype: review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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