Role of Sirt3 in mitochondrial biogenesis and developmental competence of human in vitro matured oocytes.

Study Question: Does Sirt3 dysfunction result in poor developmental outcomes for human oocytes after in vitro maturation (IVM)? Summary Answer: Inefficient Sirt3 expression induced decreased mitochondrial DNA copy number and biogenesis, and therefore impaired the developmental competence of human IV...

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Publicado en:	Human Reproduction Vol. 31; no. 3; pp. 607 - 623
Autores principales:	Hong-Cui Zhao, Ting Ding, Yun Ren, Tian-Jie Li, Rong Li, Yong Fan, Jie Yan, Yue Zhao, Mo Li, Yang Yu, Jie Qiao, Zhao, Hong-Cui, Ding, Ting, Ren, Yun, Li, Tian-Jie, Li, Rong, Fan, Yong, Yan, Jie, Zhao, Yue, Li, Mo
Formato:	research Journal Article
Publicado:	Oxford University Press / USA Mar2016
Acceso en línea:	Ver este registro en EBSCOhost