Psychometric Properties of the Memory Binding Test: Test-Retest Reliability and Convergent Validity.

Background: Episodic memory testing is fundamental for the diagnosis of Alzheimer's disease (AD). Although the Free and Cued Selective Reminding Test (FCSRT) is widely used for this purpose, it may not be sensitive enough for early detection of subtle decline in preclinical AD. The Memory Binding Te...

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Publicado en:Journal of Alzheimer's Disease Vol. 50; no. 4; pp. 999 - 1011
Autores principales: Gramunt, Nina, Sánchez-Benavides, Gonzalo, Buschke, Herman, Lipton, Richard B., Masramon, Xavier, Gispert, Juan D., Peña-Casanova, Jordi, Fauria, Karine, Molinuevo, José L.
Formato: research Journal Article
Publicado: Sage Publications Inc. 2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2016
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      pub: Sage Publications Inc.
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        atl: Psychometric Properties of the Memory Binding Test: Test-Retest Reliability and Convergent Validity.
      aug:
        au:
          Gramunt, Nina
          Sánchez-Benavides, Gonzalo
          Buschke, Herman
          Lipton, Richard B.
          Masramon, Xavier
          Gispert, Juan D.
          Peña-Casanova, Jordi
          Fauria, Karine
          Molinuevo, José L.
        affil: Clinical Research Program, Barcelonafteta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain
      sug:
        subj:
          Memory
          Psychological Tests
          Middle Age
          Female
          Psychometrics
          Alzheimer's Disease Diagnosis
          Male
          Reproducibility of Results
          Aged
          Human
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Funding Source
          Questionnaires
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: Background: Episodic memory testing is fundamental for the diagnosis of Alzheimer's disease (AD). Although the Free and Cued Selective Reminding Test (FCSRT) is widely used for this purpose, it may not be sensitive enough for early detection of subtle decline in preclinical AD. The Memory Binding Test (MBT) intends to overcome this limitation.Objectives: To analyze the test-retest reliability of the MBT and its convergent validity with the FCRST.Methods: 36 cognitively healthy participants of the ALFA Study, aged 45 to 65, were included for the test-retest study and 69 for the convergent analysis. They were visited twice in a period of 6 ± 2 weeks. Test-retest reliability was determined by the calculation of the intra-class correlation coefficient (ICC). Score differences were studied by computing the mean percentage of score variation between visits and visualized by Bland-Altman plots. Convergent validity was determined by Pearson's correlations.Results: ICC values in the test-retest reliability analysis of the MBT direct scores ranged from 0.64 to 0.76. Subjects showed consistent practice effects, with mean amounts of score increasing between 10% and 26%. Pearson correlation between MBT and FCSRT direct scores showed r values between 0.40 and 0.53. The FCSRT displayed ceiling effects not observed in the MBT.Conclusions: The MBT shows adequate test-retest reliability and overall moderate convergent validity with the FCSRT. Unlike the FCSRT, the MBT does not have ceiling effects and it may therefore be especially useful in longitudinal studies, facilitating the measurement of subtle memory performance decline and the detection of very early AD.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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