Thoracic and abdominal aortic diameters in a general population: MRI-based reference values and association with age and cardiovascular risk factors.
Objectives: To generate reference values for thoracic and abdominal aortic diameters determined by magnetic resonance imaging (MRI) and analyse their association with cardiovascular risk factors in the general population.Methods: Data from participants (n = 1759) of the Study of Health in Pomerania...
| Publicado en: | European Radiology Vol. 26; no. 4; pp. 969 - 979 |
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| Autores principales: | , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Apr2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113486837&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 113486837 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Apr2016 vid: 26 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 113486837 113486837 NLM26208859 113486837 10.1007/s00330-015-3926-6 NLM26208859 113486837 ppf: 969 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Thoracic and abdominal aortic diameters in a general population: MRI-based reference values and association with age and cardiovascular risk factors. aug: au: Mensel, Birger Heßelbarth, Lydia Wenzel, Michael Kühn, Jens-Peter Dörr, Marcus Völzke, Henry Lieb, Wolfgang Hegenscheid, Katrin Lorbeer, Roberto affil: Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße 17475 Greifswald Germany sug: subj: Aorta, Abdominal Anatomy and Histology Aorta, Thoracic Anatomy and Histology Cardiovascular Diseases Etiology Aging Male Middle Age Blood Pressure Physiology Smoking Pathology Lipoproteins, HDL Cholesterol Metabolism Smoking Magnetic Resonance Angiography Linear Regression Adult Cross Sectional Studies Reference Values Risk Factors Female Body Surface Area Aged Cardiovascular Diseases Pathology Human Middle Aged: 45-64 years Adult: 19-44 years Aged: 65+ years Male Female ab: Objectives: To generate reference values for thoracic and abdominal aortic diameters determined by magnetic resonance imaging (MRI) and analyse their association with cardiovascular risk factors in the general population.Methods: Data from participants (n = 1759) of the Study of Health in Pomerania were used for analysis in this study. MRI measurement of thoracic and abdominal aortic diameters was performed. Parameters for calculation of reference values according to age and sex analysis were provided. Multivariable linear regression models were used for determination of aortic diameter-related risk factors, including smoking, blood pressure (BP), high-density lipoprotein cholesterol (HDL-C).Results: For the ascending aorta (β = -0.049, p < 0.001), the aortic arch (β = -0.061, p < 0.001) and the subphrenic aorta (β = -0.018, p = 0.004), the body surface area (BSA)-adjusted diameters were lower in men. Multivariable-adjusted models revealed significant increases in BSA-adjusted diameters with age for all six aortic segments (p < 0.001). Consistent results for all segments were observed for the positive associations of diastolic BP (β = 0.001; 0.004) and HDL (β = 0.035; 0.087) with BSA-adjusted aortic diameters and for an inverse association of systolic BP (β = -0.001).Conclusions: Some BSA-adjusted median aortic diameters are smaller in men than in women. All diameters increase with age, diastolic blood pressure and HDL-C and decrease as systolic BP increases.Key Points: • Median aortic diameter increases with age and diastolic blood pressure. • Median aortic diameter is larger in men than in women. • Some BSA-adjusted median aortic diameters are smaller in men than in women. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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