Real-time phase contrast magnetic resonance imaging for assessment of haemodynamics: from phantom to patients.
Objectives: Assessment of haemodynamics is crucial in many cardiac diseases. Phase contrast MRI (PC-MRI) can accurately access it. Arrhythmia is a major limitation in conventional segmented PC-MRI (SEG). A real-time PC-MRI sequence (RT) could overcome this. We validated RT by comparing to SEG.Method...
| Publicado en: | European Radiology Vol. 26; no. 4; pp. 986 - 997 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Apr2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113486863&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 113486863 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Apr2016 vid: 26 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 113486863 113486863 NLM26188655 113486863 10.1007/s00330-015-3897-7 NLM26188655 113486863 ppf: 986 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Real-time phase contrast magnetic resonance imaging for assessment of haemodynamics: from phantom to patients. aug: au: Traber, Julius Wurche, Lennart Dieringer, Matthias Utz, Wolfgang Knobelsdorff-Brenkenhoff, Florian Greiser, Andreas Jin, Ning Schulz-Menger, Jeanette Dieringer, Matthias A von Knobelsdorff-Brenkenhoff, Florian affil: Department of Cardiology and Nephrology, Working Group on Cardiovascular Magnetic Resonance Imaging, Experimental and Clinical Research Center, Max-Delbrück-Centrum and Charité -Medical University Berlin and HELIOS Klinikum Berlin-Buch, Schwanebecker Chaussee 50 13125 Berlin Germany sug: subj: Hemodynamics Physiology Atrial Fibrillation Physiopathology Aortic Valve Physiopathology Pulmonary Artery Physiology Stroke Volume Physiology Heart Defects, Congenital Physiopathology Aged Phantoms, Imaging Female Human Male Aorta Physiology Microscopy Equipment and Supplies Middle Age Magnetic Resonance Angiography Equipment and Supplies Microscopy Methods Blood Flow Velocity Physiology Aortic Valve Stenosis Physiopathology Aortic Valve Insufficiency Physiopathology Heart Valve Diseases Physiopathology Magnetic Resonance Angiography Methods Validation Studies Comparative Studies Evaluation Research Multicenter Studies Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objectives: Assessment of haemodynamics is crucial in many cardiac diseases. Phase contrast MRI (PC-MRI) can accurately access it. Arrhythmia is a major limitation in conventional segmented PC-MRI (SEG). A real-time PC-MRI sequence (RT) could overcome this. We validated RT by comparing to SEG.Methods: A prototype RT using shared velocity encoding was tested against SEG at 1.5 T in a flow phantom and consecutively included patients with (n = 55) or without (n = 59) aortic valve disease. In patients with atrial fibrillation (Afib, n = 15), only RT was applied. Phantom: PC images were acquired in front of and behind an interchangeable aortic-stenosis-like inlay. Mean velocity and flow were quantified.Patients: PC images were acquired in the ascending aorta, pulmonary trunk and superior caval vein. Peak velocity, stroke volume and regurgitant fraction were quantified.Results: Phantom: Mean velocities (11 ± 1 to 207 ± 10 cm/s) and flow correlated closely between SEG and RT (r ≥ 0.99, ICC ≥ 0.98, p < 0.0005). Patients without AVD or with aortic regurgitation: Concordance of SEG and RT was excellent regarding peak velocities, stroke volumes (r ≥ 0.91, ICC ≥ 0.94, p < 0.0005) and regurgitant fractions (r = 0.95, ICC = 0.95, p < 0.0005). RT was feasible in all patients with Afib.Conclusions: The real-time sequence is accurate compared to conventional segmented PC-MRI. Its applicability in Afib was shown. Real-time PC-MRI might become a valuable tool in arrhythmia.Key Points: • Assessment of haemodynamics is crucial in many cardiac diseases. • Arrhythmias are a major limitation of conventional techniques in cardiac magnetic resonance. • A real-time technique, which allows application in arrhythmia, was validated. • This real-time technique might become a valuable tool in arrhythmic patients. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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