Alteration of Regional Homogeneity within the Sensorimotor Network after Spinal Cord Decompression in Cervical Spondylotic Myelopathy: A Resting-State fMRI Study.

There is a lack of longitudinal research to evaluate the function of neurons’ adaptive changes within the sensorimotor network (SMN) following recovery after cervical cord decompression. Regional homogeneity (ReHo) may provide information that is critical to fully understand CSM-related functional n...

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Publicado en:BioMed Research International Vol. 2015; pp. 1 - 7
Autores principales: Tan, Yongming, Zhou, Fuqing, Wu, Lin, Liu, Zhili, Zeng, Xianjun, Gong, Honghan, He, Laichang
Formato: research Journal Article
Publicado: Wiley-Blackwell 10/29/2015
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 10/29/2015
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2015/647958
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        atl: Alteration of Regional Homogeneity within the Sensorimotor Network after Spinal Cord Decompression in Cervical Spondylotic Myelopathy: A Resting-State fMRI Study.
      aug:
        au:
          Tan, Yongming
          Zhou, Fuqing
          Wu, Lin
          Liu, Zhili
          Zeng, Xianjun
          Gong, Honghan
          He, Laichang
        affil: Department of Radiology, The First Affiliated Hospital of Nanchang University, Yong Wai Street, No. 17, Nanchang, Jiangxi 330006, China
      sug:
        subj:
          Magnetic Resonance Imaging
          Spondylosis
          Spinal Cord Abnormalities
          Neurons
          Cervical Cord Abnormalities
          Human
          Prospective Studies
      ab: There is a lack of longitudinal research to evaluate the function of neurons’ adaptive changes within the sensorimotor network (SMN) following recovery after cervical cord decompression. Regional homogeneity (ReHo) may provide information that is critical to fully understand CSM-related functional neural synchrony alterations. The purpose of this study was to assess the ReHo alterations of resting state-functional MRI (rs-fMRI) within pre- and postdecompression CSM and healthy controls (HC) and its correlations with clinical indices. Predecompression CSM demonstrated a significantly lower ReHo in the left primary sensory cortex and primary motor cortex (PostG/PreG) but enhanced ReHo in the right superior parietal lobule (SPL) compared with HC. In comparison with predecompression CSM, the postdecompression CSM showed increased ReHo in the left PostG/PreG but significantly lower ReHo in the right SPL compared with HC patients. Abnormal ReHo regions in pre- or postdecompression CSM showed no significant correlation with the Japanese Orthopaedic Association (JOA) scores, Neck Disability Index (NDI) scores, and disease duration (P>0.05). This result demonstrated disrupted regional homogeneity within SMN in CSM. This adaptive change in the brain may favor the preservation of sensorimotor networks before and after cervical cord decompression and clinical symptoms independent of ReHo within SMN.
      pubtype: Academic Journal
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        research
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    language: English
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