The Importance of the Training-Induced Decrease in Basal Cortisol Concentration in the Improvement in Muscular Performance in Humans.

Acute exercise-induced changes in cortisol concentration (C) and training related adaptation within hypothalamic-pituitary-adrenal (HPA) axis has been widely examined, but their influence on muscle strength performance is at best uncertain. Twenty four young healthy men were randomly assigned to an...

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Publicado en:Physiological Research Vol. 65; no. 1; pp. 109 - 121
Autores principales: GRANDYS, M., MAJERCZAK, J., KULPA, J., DUDA, K., RYCHLIK, U., ZOLADZ, J. A.
Formato: Journal Article
Publicado: Institute of Physiology, Academy of Sciences of the Czech Republic 2016
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Institute of Physiology, Academy of Sciences of the Czech Republic
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        atl: The Importance of the Training-Induced Decrease in Basal Cortisol Concentration in the Improvement in Muscular Performance in Humans.
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          GRANDYS, M.
          MAJERCZAK, J.
          KULPA, J.
          DUDA, K.
          RYCHLIK, U.
          ZOLADZ, J. A.
        affil: Department of Muscle Physiology, Chair of Physiology and Biochemistry, Faculty of Rehabilitation, University School of Physical Education, Krakow, Poland
      sug:
      ab: Acute exercise-induced changes in cortisol concentration (C) and training related adaptation within hypothalamic-pituitary-adrenal (HPA) axis has been widely examined, but their influence on muscle strength performance is at best uncertain. Twenty four young healthy men were randomly assigned to an endurance training group (ET, n=12) or to a non-exercising controls (CON, n=12). ET performed supervised endurance training on cycle ergometer for 20 weeks. Endurance training program improved exercise capacity (14 % increase in power output generated at peak oxygen uptake - VO2peak), muscle strength performance (increase in MVC - maximal voluntary contraction - by 9 % and in TTF 50 % MVC - time to fatigue at 50 % MVC - by 21 %) and led to a decrease in basal serum C concentration (P=0.006) and an increase in basal testosterone to cortisol (T/C) and free testosterone to cortisol (fT/C) ratios (P=0.01 and P=0.02, respectively). It was found that the decrease in C concentration (▵ C) was positively correlated to the increase in local muscular endurance (▵ TTF 50 % MVC). No significant hormonal changes were seen in CON group. It is concluded that greater decrease in cortisol concentration after the endurance training is accompanied by poorer improvement in skeletal muscle performance in previously untrained subjects.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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