A sinogram warping strategy for pre-reconstruction 4D PET optimization.

A novel strategy for 4D PET optimization in the sinogram domain is proposed, aiming at motion model application before image reconstruction ("sinogram warping" strategy). Compared to state-of-the-art 4D-MLEM reconstruction, the proposed strategy is able to optimize the image SNR, avoiding iterative...

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Published in:Medical & Biological Engineering & Computing Vol. 54; no. 2/3; pp. 535 - 547
Main Authors: Gianoli, Chiara, Riboldi, Marco, Fontana, Giulia, Kurz, Christopher, Parodi, Katia, Baroni, Guido
Format: diagnostic images equations & formulas research tables/charts Journal Article
Published: Springer Nature Mar2016
Online Access:View this record in EBSCOhost
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      dt: Mar2016
      vid: 54
      iid: 2/3
      pid: 237
      pub: Springer Nature
      place: New York, New York
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        atl: A sinogram warping strategy for pre-reconstruction 4D PET optimization.
      aug:
        au:
          Gianoli, Chiara
          Riboldi, Marco
          Fontana, Giulia
          Kurz, Christopher
          Parodi, Katia
          Baroni, Guido
        affil: Bioengineering Unit, National Center for Oncologic Hadrontherapy (CNAO), Strada Privata Campeggi 53 27100 Pavia Italy
      sug:
        subj:
          Algorithms
          Image Processing, Computer Assisted Methods
          Tomography, Emission-Computed Methods
          Motion
          Tomography, X-Ray Computed
          Models, Theoretical
          Phantoms, Imaging
          Immunity
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
      ab: A novel strategy for 4D PET optimization in the sinogram domain is proposed, aiming at motion model application before image reconstruction ("sinogram warping" strategy). Compared to state-of-the-art 4D-MLEM reconstruction, the proposed strategy is able to optimize the image SNR, avoiding iterative direct and inverse warping procedures, which are typical of the 4D-MLEM algorithm. A full-count statistics sinogram of the motion-compensated 4D PET reference phase is generated by warping the sinograms corresponding to the different PET phases. This is achieved relying on a motion model expressed in the sinogram domain. The strategy was tested on the anthropomorphic 4D PET-CT NCAT phantom in comparison with the 4D-MLEM algorithm, with particular reference to robustness to PET-CT co-registrations artefacts. The MLEM reconstruction of the warped sinogram according to the proposed strategy exhibited better accuracy (up to +40.90 % with respect to the ideal value), whereas images reconstructed according to the 4D-MLEM reconstruction resulted in less noisy (down to -26.90 % with respect to the ideal value) but more blurred. The sinogram warping strategy demonstrates advantages with respect to 4D-MLEM algorithm. These advantages are paid back by introducing approximation of the deformation field, and further efforts are required to mitigate the impact of such an approximation in clinical 4D PET reconstruction.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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