Sound transmission in porcine thorax through airway insonification.
Many pulmonary injuries and pathologies may lead to structural and functional changes in the lungs resulting in measurable sound transmission changes on the chest surface. Additionally, noninvasive imaging of externally driven mechanical wave motion in the chest (e.g., using magnetic resonance elast...
| Published in: | Medical & Biological Engineering & Computing Vol. 54; no. 4; pp. 675 - 690 |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | equations & formulas pictorial research tables/charts Journal Article |
| Published: |
Springer Nature
Apr2016
|
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113881204&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 113881204 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Apr2016 vid: 54 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 113881204 113881204 NLM26280512 113881204 10.1007/s11517-015-1358-8 NLM26280512 PMC4758916 [Available on 04/01/17] 113881204 ppf: 675 ppct: 15 formats: fmt: @attributes: type: P tig: atl: Sound transmission in porcine thorax through airway insonification. aug: au: Peng, Ying Dai, Zoujun Mansy, Hansen Henry, Brian Sandler, Richard Balk, Robert Royston, Thomas Mansy, Hansen A Henry, Brian M Sandler, Richard H Balk, Robert A Royston, Thomas J affil: Department of Mechanical and Industrial Engineering, University of Illinois at Chicago, 842 W. Taylor St, 2039 ERF Chicago 60607 USA sug: subj: Thorax Physiology Lung Physiology Sound Animal Studies Models, Anatomic Swine Motion Imaging, Three-Dimensional Pneumothorax Physiopathology Acoustics Computer Simulation Funding Source ab: Many pulmonary injuries and pathologies may lead to structural and functional changes in the lungs resulting in measurable sound transmission changes on the chest surface. Additionally, noninvasive imaging of externally driven mechanical wave motion in the chest (e.g., using magnetic resonance elastography) can provide information about lung structural property changes and, hence, may be of diagnostic value. In the present study, a comprehensive computational simulation (in silico) model was developed to simulate sound wave propagation in the airways, lung, and chest wall under normal and pneumothorax conditions. Experiments were carried out to validate the model. Here, sound waves with frequency content from 50 to 700 Hz were introduced into airways of five porcine subjects via an endotracheal tube, and transmitted waves were measured by scanning laser Doppler vibrometry at the chest wall surface. The computational model predictions of decreased sound transmission with pneumothorax were consistent with experimental measurements. The in silico model can also be used to visualize wave propagation inside and on the chest wall surface for other pulmonary pathologies, which may help in developing and interpreting diagnostic procedures that utilize sound and vibration. pubtype: Academic Journal doctype: equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|