Skin Signs of Rheumatoid Arthritis and its Therapy-Induced Cutaneous Side Effects.

Rheumatoid arthritis (RA) is a systemic inflammatory disorder that primarily affects the joints, but may exhibit extra-articular, including cutaneous, manifestations such as rheumatoid nodules, rheumatoid vasculitis, granulomatous skin disorders, and neutrophilic dermatoses. A large burden of cutane...

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Publicado en:American Journal of Clinical Dermatology Vol. 17; no. 2; pp. 147 - 163
Autores principales: Xue, Yun, Cohen, Jeffrey, Wright, Natalie, Merola, Joseph
Formato: pictorial review tables/charts Journal Article
Publicado: Springer Nature Apr2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2016
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      pub: Springer Nature
      place: New York, New York
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        atl: Skin Signs of Rheumatoid Arthritis and its Therapy-Induced Cutaneous Side Effects.
      aug:
        au:
          Xue, Yun
          Cohen, Jeffrey
          Wright, Natalie
          Merola, Joseph
        affil: Department of Dermatology, Brigham and Women's Hospital and Harvard Medical School, 41 Avenue Louis Pasteur, Suite 319 Boston 02115 USA
      sug:
        subj:
          Arthritis, Rheumatoid Drug Therapy
          Arthritis, Rheumatoid Complications
          Skin Diseases Etiology
          Vasculitis
          Sweet's Syndrome
          Pyoderma Gangrenosum
          Felty's Syndrome
          Drugs, Prescription Adverse Effects
      ab: Rheumatoid arthritis (RA) is a systemic inflammatory disorder that primarily affects the joints, but may exhibit extra-articular, including cutaneous, manifestations such as rheumatoid nodules, rheumatoid vasculitis, granulomatous skin disorders, and neutrophilic dermatoses. A large burden of cutaneous disease may be an indication of RA disease activity and the need for more aggressive treatment. Many of the therapeutic agents used to treat RA can also result in cutaneous adverse effects, which pose their own diagnostic and therapeutic challenges. Anti-TNFα agents, in particular, have a wide variety of adverse effects including psoraisiform eruptions, granulomatous conditions, and cutaneous connective tissue disorders. Herein we provide an update on the clinical presentations and management of RA-associated cutaneous findings as well as drug-induced cutaneous effects, with particular attention to the adverse effects of biologic disease-modifying agents.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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