Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates.
We developed a two-step chemical bonding process using photosensitizer molecules to fabricate photofunctional nanolayer coatings on hematoporphyrin- (HP-) coated Ti substrates. In the first step, 3-aminopropyltriethoxysilane was covalently functionalized onto the surface of the Ti substrates to prov...
| Publicado en: | BioMed Research International Vol. 2016; pp. 1 - 10 |
|---|---|
| Autores principales: | , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
3/24/2016
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=113954488&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 113954488 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 3/24/2016 vid: 2016 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 113954488 113954488 113954488 10.1155/2016/4318917 113954488 ppf: 1 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates. aug: au: Choi, Kyong-Hoon Kim, Jung-Gil Kang, Byungman Kim, Ho-Joong Park, Bong Joo affil: Plasma Bioscience Research Center, Kwangwoon University, 20 Kwangwoon-gil, Nowon-gu, Seoul 139-701, Republic of Korea sug: subj: Nanostructures Titanium Nanotechnology Prostheses and Implants Chemistry, Physical Porphyrins Silicon Compounds Spectrometry, X-Ray Emission Microscopy, Electron, Scanning Spectrophotometry Methods Heterocyclic Compounds Materials Testing Toxicity Tests Oxygen Cell Culture Techniques T-Tests P-Value Descriptive Statistics Animal Studies Mice Funding Source ab: We developed a two-step chemical bonding process using photosensitizer molecules to fabricate photofunctional nanolayer coatings on hematoporphyrin- (HP-) coated Ti substrates. In the first step, 3-aminopropyltriethoxysilane was covalently functionalized onto the surface of the Ti substrates to provide heterogeneous sites for immobilizing the HP molecules. Then, HP molecules with carboxyl groups were chemically attached to the amine-terminated nanolayer coatings via a carbodiimide coupling reaction. The microstructure and elemental and phase composition of the HP-coated Ti substrates were investigated using field-emission scanning electron microscopy and energy-dispersive X-ray spectrometry. The photophysical properties of the photofunctional nanolayer coatings were confirmed using reflectance ultraviolet-visible absorption and emission spectrophotometry. The singlet oxygen generation efficiency of the photofunctional nanolayer coatings was determined using the decomposition reaction of 1,3-diphenylisobenzofuran. The HP-coated Ti substrates exhibited good biocompatibility without any cytotoxicity, and these nanolayer coatings generated singlet oxygen, which can kill microorganisms using only visible light. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|