Development and validation of an automated and marker-free CT-based spatial analysis method (CTSA) for assessment of femoral hip implant migration In vitro accuracy and precision comparable to that of radiostereometric analysis (RSA).

Background and purpose — We developed a marker-free automated CT-based spatial analysis (CTSA) method to detect stem-bone migration in consecutive CT datasets and assessed the accuracy and precision in vitro. Our aim was to demonstrate that in vitro accuracy and precision of CTSA is comparable to th...

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Published in:Acta Orthopaedica Vol. 87; no. 2; pp. 139 - 146
Main Authors: Scheerlinck, Thierry, Polfliet, Mathias, Deklerck, Rudi, Van Gompel, Gert, Buls, Nico, Vandemeulebroucke, Jef
Format: diagnostic images pictorial research tables/charts Journal Article
Published: Medical Journals Sweden AB Apr2016
Online Access:View this record in EBSCOhost
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      dt: Apr2016
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      pub: Medical Journals Sweden AB
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        10.3109/17453674.2015.1123569
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        atl: Development and validation of an automated and marker-free CT-based spatial analysis method (CTSA) for assessment of femoral hip implant migration In vitro accuracy and precision comparable to that of radiostereometric analysis (RSA).
      aug:
        au:
          Scheerlinck, Thierry
          Polfliet, Mathias
          Deklerck, Rudi
          Van Gompel, Gert
          Buls, Nico
          Vandemeulebroucke, Jef
        affil: Department or Orthopedic Surgery and Traumatology, Universitair Ziekenhuis Brussel, Brussels
      sug:
        subj:
          Tomography, X-Ray Computed Methods
          Prosthesis Failure Radiography
          Prostheses and Implants
          Femur Radiography
          Hip Radiography
          Human
          Validity
          Precision
          Radiostereometric Analysis
          In Vitro Studies
          Validation Studies
          Orthopedic Fixation Devices
          Dislocations
          Rotation
          Descriptive Statistics
          Comparative Studies
      ab: Background and purpose — We developed a marker-free automated CT-based spatial analysis (CTSA) method to detect stem-bone migration in consecutive CT datasets and assessed the accuracy and precision in vitro. Our aim was to demonstrate that in vitro accuracy and precision of CTSA is comparable to that of radiostereometric analysis (RSA). Material and methods — Stem and bone were segmented in 2 CT datasets and both were registered pairwise. The resulting rigid transformations were compared and transferred to an anatomically sound coordinate system, taking the stem as reference. This resulted in 3 translation parameters and 3 rotation parameters describing the relative amount of stem-bone displacement, and it allowed calculation of the point of maximal stem migration. Accuracy was evaluated in 39 comparisons by imposing known stem migration on a stem-bone model. Precision was estimated in 20 comparisons based on a zero-migration model, and in 5 patients without stem loosening. Results — Limits of the 95% tolerance intervals (TIs) for accuracy did not exceed 0.28 mm for translations and 0.20° for rotations (largest standard deviation of the signed error (SDSE): 0.081 mm and 0.057°). In vitro, limits of the 95% TI for precision in a clinically relevant setting (8 comparisons) were below 0.09 mm and 0.14° (largest SDSE: 0.012 mm and 0.020°). In patients, the precision was lower, but acceptable, and dependent on CT scan resolution. Interpretation — CTSA allows detection of stem-bone migration with an accuracy and precision comparable to that of RSA. It could be valuable for evaluation of subtle stem loosening in clinical practice.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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