MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.

Meningioma-1 (MN1) overexpression is frequently observed in patients with acute myeloid leukemia (AML) and is predictive of poor prognosis. In murine models, forced expression of MN1 in hematopoietic progenitors induces an aggressive myeloid leukemia that is strictly dependent on a defined gene expr...

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Bibliographic Details

Published in:	Journal of Clinical Investigation Vol. 126; no. 4; pp. 1438 - 1451
Main Authors:	Riedel, Simone S., Haladyna, Jessica N., Bezzant, Matthew, Stevens, Brett, Pollyea, Daniel A., Sinha, Amit U., Armstrong, Scott A., Qi Wei, Pollock, Roy M., Daigle, Scott R., Jordan, Craig T., Ernst, Patricia, Neff, Tobias, Bernt, Kathrin M., Wei, Qi
Format:	Journal Article
Published:	American Society for Clinical Investigation Apr2016
Online Access:	View this record in EBSCOhost