A randomized controlled bicenter trial of yoga for patients with colorectal cancer.
Objective: The aim of this trial was to evaluate the effects of yoga on health-related quality of life in patients with colorectal cancer.Methods: Patients with non-metastatic colorectal cancer were randomly assigned to a 10-week yoga intervention (90 min once weekly) or a waitlist control group. Pr...
| Published in: | Psycho-Oncology Vol. 25; no. 4; pp. 412 - 421 |
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| Main Authors: | , , , , , , , , , , , |
| Format: | research randomized controlled trial Journal Article |
| Published: |
Wiley-Blackwell
Apr2016
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=114246052&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 114246052 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10579249 O9K jtl: Psycho-Oncology issn: 10579249 maglogo: Y pubinfo: dt: Apr2016 vid: 25 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 114246052 114246052 NLM26228466 114246052 10.1002/pon.3927 NLM26228466 114246052 ppf: 412 ppct: 9 formats: tig: atl: A randomized controlled bicenter trial of yoga for patients with colorectal cancer. aug: au: Cramer, Holger Pokhrel, Bijay Fester, Claudia Meier, Beate Gass, Florian Lauche, Romy Eggleston, Brandon Walz, Martin Michalsen, Andreas Kunz, Reiner Dobos, Gustav Langhorst, Jost affil: Department of Internal and Integrative Medicine, Kliniken Essen‐Mitte, Faculty of Medicine, University of Duisburg‐Essen, Essen Germany sug: subj: Health Status Yoga Colorectal Neoplasms Therapy Quality of Life Meditation Anxiety Therapy Colorectal Neoplasms Psychosocial Factors Treatment Outcomes Human Adult Aged Middle Age Depression Therapy Aged, 80 and Over Female Male Fatigue Therapy Self-Efficacy Validation Studies Comparative Studies Evaluation Research Multicenter Studies Randomized Controlled Trials Clinical Assessment Tools Psychological Tests Scales Questionnaires Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Aged, 80 & over Female Male ab: Objective: The aim of this trial was to evaluate the effects of yoga on health-related quality of life in patients with colorectal cancer.Methods: Patients with non-metastatic colorectal cancer were randomly assigned to a 10-week yoga intervention (90 min once weekly) or a waitlist control group. Primary outcome measure was disease-specific quality of life (Functional Assessment of Cancer Therapy - Colorectal [FACT-C]) at week 10. Secondary outcome measures included FACT-C subscales: spiritual well-being (FACT - Spirituality); fatigue (FACT - Fatigue); sleep disturbances (Pittsburgh Sleep Quality Inventory); depression and anxiety (Hospital Anxiety and Depression Scale); body awareness (Scale of Body Connection); and body-efficacy expectations (Body-Efficacy Expectations Scale). Outcomes were assessed at week 10 and week 22 after randomization.Results: Fifty-four patients (mean age 68.3 ± 9.7 years) were randomized to yoga (n = 27; attrition rate 22.2%) and control group (n = 27; attrition rate 18.5%). Patients in the yoga group attended a mean of 5.3 ± 4.0 yoga classes. No significant group differences for the FACT-C total score were found. Group differences were found for emotional well-being at week 22 (∆ = 1.59; 95% CI = 0.27,2.90; p = 0.019), sleep disturbances at week 22 (∆ = -1.08; 95% CI = -2.13, -0.03; p = 0.043), anxiety at week 10 (∆ = -1.14; 95% CI = -2.20, -0.09; p = 0.043), and depression at week 10 (∆ = -1.34; 95% CI = -2.61, -0.8; p = 0.038). No serious adverse events occurred in the yoga group, while liver metastases were diagnosed in one patient in the control group.Conclusion: This randomized trial found no effects of yoga on health-related quality of life in patients with colorectal cancer. Given the high attrition rate and low intervention adherence, no definite conclusions can be drawn from this trial. pubtype: Academic Journal doctype: research randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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