Programmed Death Ligand-1 Immunohistochemistry--A New Challenge for Pathologists.

The binding of programmed death ligand-1 and ligand-2 (PD-L1 and PD-L2) to PD-1 blocks T-cell-mediated immune response to tumor. Antibodies that target programmed death receptor-1 (PD-1) will block the ligand-receptor interface, thereby allowing T cells to attack the tumor and increase antitumor imm...

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Publicado en:Archives of Pathology & Laboratory Medicine Vol. 140; no. 4; pp. 341 - 345
Autores principales: Sholl, Lynette M., Aisner, Dara L., Craig Allen, Timothy, Beasley, Mary Beth, Borczuk, Alain C., Cagle, Philip T., Capelozzi, Vera, Dacic, Sanja, Hariri, Lida, Kerr, Keith M., Lantuejoul, Sylvie, Mino-Kenudson, Mari, Raparia, Kirtee, Rekhtman, Natasha, Roy-Chowdhuri, Sinchita, Thunnissen, Eric, Ming Sound Tsao, Yasushi Yatabe
Formato: tables/charts Journal Article
Publicado: College of American Pathologists Apr2016
Acceso en línea:Ver este registro en EBSCOhost