Noninvasive Estimation of Epicardial Dominant High-Frequency Regions During Atrial Fibrillation.

Noninvasive Estimation of Fibrillation Frequencies Introduction Ablation of high dominant frequency (DF) sources in patients with atrial fibrillation (AF) is an effective treatment option for paroxysmal AF. The aim of this study was to evaluate the accuracy of noninvasive estimation of DF and electr...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 27; no. 4; pp. 435 - 443
Autores principales: PEDRÓN‐TORRECILLA, JORGE, RODRIGO, MIGUEL, CLIMENT, ANDREU M., LIBEROS, ALEJANDRO, PÉREZ‐DAVID, ESTHER, BERMEJO, JAVIER, ARENAL, ÁNGEL, MILLET, JOSÉ, FERNÁNDEZ‐AVILÉS, FRANCISCO, BERENFELD, OMER, ATIENZA, FELIPE, GUILLEM, MARÍA S.
Formato: equations & formulas pictorial research tables/charts tracings Journal Article
Publicado: Wiley-Blackwell Apr2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2016
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/jce.12931
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          PEDRÓN‐TORRECILLA, JORGE
          RODRIGO, MIGUEL
          CLIMENT, ANDREU M.
          LIBEROS, ALEJANDRO
          PÉREZ‐DAVID, ESTHER
          BERMEJO, JAVIER
          ARENAL, ÁNGEL
          MILLET, JOSÉ
          FERNÁNDEZ‐AVILÉS, FRANCISCO
          BERENFELD, OMER
          ATIENZA, FELIPE
          GUILLEM, MARÍA S.
        affil: ITACA, Universitat Politècnica de València, Valencia Spain
      sug:
        subj:
          Atrial Fibrillation Diagnosis
          Heart Atrium Innervation
          Body Surface Potential Mapping Methods
          Noninvasive Procedures
          Cardiac Patients
          Models, Statistical
          Comparative Studies
          Human
          Atrial Fibrillation Surgery
          Catheter Ablation
          Male
          Adult
          Middle Age
          Tomography, X-Ray Computed
          Action Potentials
          Computer Simulation
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
      ab: Noninvasive Estimation of Fibrillation Frequencies Introduction Ablation of high dominant frequency (DF) sources in patients with atrial fibrillation (AF) is an effective treatment option for paroxysmal AF. The aim of this study was to evaluate the accuracy of noninvasive estimation of DF and electrical patterns determination by solving the inverse problem of the electrocardiography. Methods Four representative AF patients with left-to-right and right-to-left atrial DF patterns were included in the study. For each patient, intracardiac electrograms from both atria were recorded simultaneously together with 67-lead body surface recordings. In addition to clinical recordings, realistic mathematical models of atria and torso anatomy with different DF patterns of AF were used. For both mathematical models and clinical recordings, inverse-computed electrograms were compared to intracardiac electrograms in terms of voltage, phase, and frequency spectrum relative errors. Results Comparison between intracardiac and inverse computed electrograms for AF patients showed 8.8 ± 4.4% errors for DF, 32 ± 4% for voltage, and 65 ± 4% for phase determination. These results were corroborated by mathematical simulations showing that the inverse problem solution was able to reconstruct the frequency spectrum and the DF maps with relative errors of 5.5 ± 4.1%, whereas the reconstruction of the electrograms or the instantaneous phase presented larger relative errors (i.e., 38 ± 15% and 48 ± 14 % respectively, P < 0.01). Conclusions Noninvasive reconstruction of atrial frequency maps can be achieved by solving the inverse problem of electrocardiography with a higher accuracy than temporal distribution patterns.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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