Estimation of dynamic metabolic activity in micro-tissue cultures from sensor recordings with an FEM model.

We estimated the dynamic cell metabolic activity and the distribution of the pH value and oxygen concentration in tissue samples cultured in vitro by using real-time sensor records and a numerical simulation of the underlying reaction-diffusion processes. As an experimental tissue model, we used chi...

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Bibliographic Details

Published in:	Medical & Biological Engineering & Computing Vol. 54; no. 5; pp. 763 - 773
Main Authors:	Pfister, Cornelia, Forstmeier, Christian, Biedermann, Johannes, Schermuly, Julia, Demmel, Franz, Wolf, Peter, Kaspers, Bernd, Brischwein, Martin
Format:	research Journal Article
Published:	Springer Nature May2016
Online Access:	View this record in EBSCOhost