Comparison of Resting Energy Expenditure Between Cancer Subjects and Healthy Controls: A Meta-Analysis.

There is conflicting evidence surrounding the extent of changes in resting energy expenditure (REE) in cancer. This meta-analysis aimed to establish the mean difference in REE, as kilojoules per kilogram fat-free mass, among cancer patients when compared to healthy control subjects. The secondary ai...

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Publicado en:Nutrition & Cancer Vol. 68; no. 3; pp. 374 - 388
Autores principales: Nguyen, Thi Yen Vi, Batterham, Marijka J., Edwards, Cheree
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Taylor & Francis Ltd Apr2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2016
      vid: 68
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      pub: Taylor & Francis Ltd
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        10.1080/01635581.2016.1153667
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        atl: Comparison of Resting Energy Expenditure Between Cancer Subjects and Healthy Controls: A Meta-Analysis.
      aug:
        au:
          Nguyen, Thi Yen Vi
          Batterham, Marijka J.
          Edwards, Cheree
        affil: School of Medicine, University of Wollongong, Wollongong, New South Wales, Australia
      sug:
        subj:
          Energy Metabolism Evaluation
          Cancer Patients Evaluation
          Meta Analysis
          Human
          Nutrition
          Control Group
          Weights and Measures
          International System of Units
          Literature Review
          Databases
          PubMed
          Cochrane Library
          Data Analysis Software
      ab: There is conflicting evidence surrounding the extent of changes in resting energy expenditure (REE) in cancer. This meta-analysis aimed to establish the mean difference in REE, as kilojoules per kilogram fat-free mass, among cancer patients when compared to healthy control subjects. The secondary aim was to determine differences among different cancer types. PubMed, Cochrane Library, Medline, Science Direct, Scopus, Web of Science, Wiley Online Library, and ProQuest Central were searched from the earliest records until March 2014. Studies were included if measured REE was reported as kilojoules or kilocalories per kilogram fat-free mass (FFM) in adult subjects with cancer. Twenty-seven studies were included in the meta-analysis. Fourteen studies included both cancer (n= 1453) and control (n= 1145) groups. The meta-analysis shows an average increase in REE of 9.66 (95% confidence interval: 3.34, 15.98) kJ/kgFFM/day in cancer patients when compared to control subjects. Heterogeneity was detected (P< 0.001) which suggest variations in REE among cancer types. Elevations are most noticeable in patients with cancers of metabolically demanding organs.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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