The Effects of Female Sex Hormones on Ventricular Premature Beats and Repolarization Parameters in Physiological Menstrual Cycle.
Background The effects of gender difference on cardiac electrophysiology have been well studied. In this study, we aimed to evaluate the effects of estradiol and progesteron changes occuring in physiological menstrual cycle on ventricular premature beats (VPBs) and cardiac repolarization parameters....
| Publicado en: | Pacing & Clinical Electrophysiology Vol. 39; no. 5; pp. 418 - 427 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
May2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=114816307&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 114816307 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: May2016 vid: 39 iid: 5 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 114816307 114816307 114816307 10.1111/pace.12821 114816307 ppf: 418 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The Effects of Female Sex Hormones on Ventricular Premature Beats and Repolarization Parameters in Physiological Menstrual Cycle. aug: au: DOGAN, MEHMET YIGINER, OMER UZ, OMER KUCUK, UGUR DEGIRMENCIOGLU, GOKHAN ISILAK, ZAFER UZUN, MEHMET DAVULCU, EZGI affil: Ankara Mevki Military Hospital, Department of Cardiology, Ankara Turkey sug: subj: Estradiol Physiology Progesterone Physiology Premature Ventricular Contractions Etiology Heart Rate Menstruation Ovulation Action Potentials Physiology Human Female Adolescence Adult Middle Age Ventricular Outflow Obstruction Complications Echocardiography Descriptive Statistics Data Analysis Software P-Value Outpatients Fisher's Exact Test McNemar's Test T-Tests Nonparametric Statistics Mann-Whitney U Test Wilcoxon Rank Sum Test Case Control Studies Academic Medical Centers Turkiye Turkiye Estradiol Blood Progesterone Blood Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Female ab: Background The effects of gender difference on cardiac electrophysiology have been well studied. In this study, we aimed to evaluate the effects of estradiol and progesteron changes occuring in physiological menstrual cycle on ventricular premature beats (VPBs) and cardiac repolarization parameters. Methods Women of reproductive age with VPBs were included into the study group and healthy women were recruited as the control group. During the menstruation period, a 12-lead electrocardiography, blood samples, and 24-hour rhythm Holter were applied to the study group. Similarly, all tests were repeated in the estimated ovulation period (12-14 days before menstruation) by all cases. Results The study group consisted of 20 women patients with VPB, and the control group of 18 healthy women. While the number of VPB in the menstruation period was 210 beats/day (interquartile range [IQR]: 1,144), it decreased to 86 beats/day (IQR: 251) in the ovulation period with statistical significance (P < 0.05). Average heart rate in the menstruation period was 81.4 ± 10 beats/min and it significantly increased to 84.6 ± 8 beats/min in the ovulation period (P < 0.05). There were no differences in cardiac repolarization parameters in both menstruation and ovulation periods between the study and control groups. Comparing the menstruation and the ovulation periods, J-Tpeak interval, which reflects early repolarization, was shorter in the ovulation period (193 ± 27.7 ms and 201.1 ± 28.6 ms, respectively; P < 0.05). Other repolarization parameters did not show any significant difference. Conclusion VPB frequency decreases with estradiol peak in the ovulation period. This suggests that estrogen may have protective effects against ventricular arrhythmias. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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