PRO-ONKO-selection of patient-reported outcome assessments for the clinical use in cancer patients-a mixed-method multicenter cross-sectional exploratory study.

Purpose: Cancer patients frequently suffer from multiple symptoms often impairing functional status and health-related quality of life (HRQOL). A comprehensive assessment including patient-reported outcomes (PROs) is recommended to enable individualized supportive care. However, PRO assessments are...

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Publicado en:Supportive Care in Cancer Vol. 24; no. 6; pp. 2503 - 2513
Autores principales: Schmidt, Heike, Merkel, Daniela, Koehler, Michael, Flechtner, Hans-Henning, Sigle, Jörg, Klinge, Bernd, Jordan, Karin, Vordermark, Dirk, Landenberger, Margarete, Jahn, Patrick
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jun2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2016
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      pub: Springer Nature
      place: New York, New York
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        atl: PRO-ONKO-selection of patient-reported outcome assessments for the clinical use in cancer patients-a mixed-method multicenter cross-sectional exploratory study.
      aug:
        au:
          Schmidt, Heike
          Merkel, Daniela
          Koehler, Michael
          Flechtner, Hans-Henning
          Sigle, Jörg
          Klinge, Bernd
          Jordan, Karin
          Vordermark, Dirk
          Landenberger, Margarete
          Jahn, Patrick
        affil: Medical Faculty, Institute of Health and Nursing Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale) Germany
      sug:
        subj:
          Neoplasms Diagnosis
          Quality of Life
          Decision Making
          Adult
          Female
          Middle Age
          Aged
          Outcome Assessment
          Neoplasms Therapy
          Cross Sectional Studies
          Study Design
          Male
          Fatigue Diagnosis
          Human
          Questionnaires
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: Purpose: Cancer patients frequently suffer from multiple symptoms often impairing functional status and health-related quality of life (HRQOL). A comprehensive assessment including patient-reported outcomes (PROs) is recommended to enable individualized supportive care. However, PRO assessments are still not part of routine clinical practice. Therefore, this project aimed to compile an item pool from validated assessment instruments to facilitate the use of PROs for clinical decision-making in oncology clinics.Methods: This qualitative dominant mixed-method cross-sectional exploratory study was carried out in four centers and comprised two stages. Stage I: Six interdisciplinary focus groups were conducted to choose questionnaires meeting particular clinical requirements. Stage II: Adult patients with heterogeneous cancer diagnoses, receiving in- or out-patient treatment were asked to participate and complete the chosen questionnaires (participation 71/74). Resulting PROs were compared with clinical records. Health care professionals (HCPs) and patients rated the usefulness for routine clinical practice.Results: The European Organisation of Research and Treatment of Cancer (EORTC) QLQ-C30 and Distress Thermometer were chosen for screening and M.D. Anderson Symptom Inventory (MDASI) and EORTC single items for monitoring. Comparison of n = 88 PRO assessments with clinical records showed consistent documentation of side effects like fever and emesis. Symptoms like fatigue, sadness, or sleep disturbance were not documented regularly in the medical records but captured by PRO assessments. Patients and HCPs judged the chosen questionnaires and electronic data collection as useful.Conclusions: Future studies should examine how PROs can complement or substitute routine documentation in order to achieve standardized assessment and documentation during the treatment process in different settings and examine possible benefits for patients.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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