Successful Use of Early Percutaneous Dilatational Tracheotomy and the No Sedation Concept in Respiratory Failure in Critically I11 Obese Subjects.

BACKGROUND: The prevalence of obesity in developed countries is rising. Currently, Europe has a prevalence of 9-30% with significant impact on public health systems. Obese patients in ICUs require special management and treatment. Altered anatomy in obese patients complicates procedures such as mech...

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Publicado en:Respiratory Care Vol. 61; no. 5; pp. 615 - 621
Autores principales: Kaese, Sven, Zander, Marie Christine, Lebiedz, Pia
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. May2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2016
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      pub: Mary Ann Liebert, Inc.
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        atl: Successful Use of Early Percutaneous Dilatational Tracheotomy and the No Sedation Concept in Respiratory Failure in Critically I11 Obese Subjects.
      aug:
        au:
          Kaese, Sven
          Zander, Marie Christine
          Lebiedz, Pia
        affil: Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany
      sug:
        subj:
          Critically Ill Patients Evaluation
          Obesity, Morbid Complications
          Respiratory Failure Risk Factors
          Respiration, Artificial Methods
          Human
          Intensive Care Units
          Retrospective Design
          Germany
          Descriptive Statistics
          Data Analysis Software
          Tracheostomy
          Male
          Female
          Adult
          Middle Age
          Aged
          Positive End-Expiratory Pressure
          Blood Gas Analysis
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: BACKGROUND: The prevalence of obesity in developed countries is rising. Currently, Europe has a prevalence of 9-30% with significant impact on public health systems. Obese patients in ICUs require special management and treatment. Altered anatomy in obese patients complicates procedures such as mechanical ventilation. Obesity affects cardiopulmonary physiology and requires elevated ventilation pressures. In our retrospective study, we determined the effect of early percutaneous dilatational tracheotomy (PDT) and cessation of sedation on respiratory parameters in severely obese subjects. METHODS: From June 2010 to July 2014, we included all subjects with a body weight of > 130 kg (body mass index >35 kg/m²) and respiratory failure who were admitted to the medical ICU of the University Hospital of Miinster. All subjects were treated with early PDT and immediate cessation of sedative drugs. We compared ventilator parameters and blood gas analysis before and after PDT. Parameters were recorded on days 0, 1, 3, and 5. Day 0 represents values during ventilation via an endotracheal tube, and days 1, 3, 5 represent values during ventilation via a tracheotomy tube. PDT was performed on day 0 after recording values during ventilation via an endotracheal tube. RESULTS: We included 23 subjects with a mean body mass index of 53.1 kg/m² and respiratory failure. After PDT and cessation of sedation, the required ventilation pressures and ... could be rapidly reduced (P < .001), whereas blood gas parameters significantly improved. We observed no severe PDT-associated complications in our cohort. CONCLUSIONS: In severe obesity, respiratory failure might be increased by problems in mechanical ventilation due to required high pressures and obesity-induced pulmonary restriction. Rapid tracheotomy with reduction of dead-space ventilation and airway resistance as well as cessation of sedation to enable spontaneous breathing might be a key factor in the therapy of respiratory failure.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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