The A, C, G, and T of Genome Assembly.

Genome assembly in its two decades of history has produced significant research, in terms of both biotechnology and computational biology. This contribution delineates sequencing platforms and their characteristics, examines key steps involved in filtering and processing raw data, explains assembly...

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Publicado en:BioMed Research International Vol. 2016; pp. 1 - 11
Autores principales: Wajid, Bilal, Sohail, Muhammad U., Ekti, Ali R., Serpedin, Erchin
Formato: review tables/charts Journal Article
Publicado: Wiley-Blackwell 5/10/2016
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 5/10/2016
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      pub: Wiley-Blackwell
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        10.1155/2016/6329217
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        atl: The A, C, G, and T of Genome Assembly.
      aug:
        au:
          Wajid, Bilal
          Sohail, Muhammad U.
          Ekti, Ali R.
          Serpedin, Erchin
        affil: Department of EE, University of Engineering & Technology, Lahore, Punjab 54890, Pakistan
      sug:
        subj:
          Genome
          Nucleotides
          Sequence Analysis Methods
          Data Collection
          Data Analysis
          Data Analysis, Statistical
          Software
          Genetic Techniques
          DNA Analysis
          Quality Assessment
      ab: Genome assembly in its two decades of history has produced significant research, in terms of both biotechnology and computational biology. This contribution delineates sequencing platforms and their characteristics, examines key steps involved in filtering and processing raw data, explains assembly frameworks, and discusses quality statistics for the assessment of the assembled sequence. Furthermore, the paper explores recent Ubuntu-based software environments oriented towards genome assembly as well as some avenues for future research.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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