Lack of contralateral suppression in transient-evoked otoacoustic emissions in multiple chemical sensitivity: a clinical correlation study.
Multiple chemical sensitivity (MCS) is a chronic disorder characterized by a variety of symptoms associated with the exposure to chemicals at a concentration below the toxic level. Previous studies have demonstrated peculiar responses in brain activity in these patients with respect to sensory stimu...
| Publicado en: | Noise & Health Vol. 18; no. 82; pp. 143 - 150 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wolters Kluwer India Pvt Ltd
May/Jun2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=115259287&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 115259287 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14631741 39SM jtl: Noise & Health issn: 14631741 maglogo: N pubinfo: dt: May/Jun2016 vid: 18 iid: 82 pid: 16919 pub: Wolters Kluwer India Pvt Ltd artinfo: ui: 115259287 115259287 NLM27157687 115259287 10.4103/1463-1741.181997 NLM27157687 PMC4918670 115259287 ppf: 143 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Lack of contralateral suppression in transient-evoked otoacoustic emissions in multiple chemical sensitivity: a clinical correlation study. aug: au: Micarelli, Alessandro Viziano, Andrea Genovesi, Giuseppe Bruno, Ernesto Ottaviani, Fabrizio Alessandrini, Marco affil: Departments of Clinical Sciences and Traslational Medicine Rome, Italy sug: subj: Auditory Perception Physiology Neural Pathways Physiology Multiple Chemical Sensitivity Physiopathology Evoked Potentials, Auditory Physiology Female Audiometry, Pure-Tone Male Otoacoustic Emissions, Spontaneous Physiology Reflex, Acoustic Physiology Middle Age Case Control Studies Multiple Chemical Sensitivity Complications Adult Human Middle Aged: 45-64 years Adult: 19-44 years Female Male ab: Multiple chemical sensitivity (MCS) is a chronic disorder characterized by a variety of symptoms associated with the exposure to chemicals at a concentration below the toxic level. Previous studies have demonstrated peculiar responses in brain activity in these patients with respect to sensory stimuli while the association between chemical sensitivity and other environmental intolerances such as noise sensitivity has been questioned by researchers. In this study, a cohort of 18 MCS patients underwent transient-evoked otoacoustic emission (TEOAE) testing with and without contralateral suppression to evaluate the functionality of the medial olivocochlear (MOC) reflex involved in speech-in-noise sensitivity. Results were compared with an age- and gender-matched control group (n = 20) and correlation analysis with disease onset and quick environmental exposure sensitivity inventory (qEESI) symptom severity scale was performed. Subjects affected by MCS showed statistically significant impairment of MOC reflex, and the onset of the disease and several symptom subscales showed to be correlated to such reduction in some of the frequencies tested. These data suggest that alterations of MOC reflex could be part of the complex features of this disease although more studies are needed to further explore auditory perception disorders in environmental intolerances. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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