Contrast-enhanced dual energy mammography with a novel anode/filter combination and artifact reduction: a feasibility study.
Objectives: To demonstrate the feasibility of contrast-enhanced dual-energy mammography (CEDEM) using titanium (Ti) filtering at 49 kVp for high-energy images and a novel artefact reducing image-subtraction post-processing algorithm.Methods: Fifteen patients with suspicious findings (ACR BI-RADS 4 a...
| Published in: | European Radiology Vol. 26; no. 6; pp. 1575 - 1582 |
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| Main Authors: | , , , , , , , , , |
| Format: | diagnostic images research tables/charts Journal Article |
| Published: |
Springer Nature
Jun2016
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=115269324&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 115269324 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jun2016 vid: 26 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 115269324 115269324 NLM26373754 115269324 10.1007/s00330-015-4007-6 NLM26373754 115269324 ppf: 1575 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Contrast-enhanced dual energy mammography with a novel anode/filter combination and artifact reduction: a feasibility study. aug: au: Knogler, Thomas Homolka, Peter Hörnig, Mathias Leithner, Robert Langs, Georg Waitzbauer, Martin Pinker-Domenig, Katja Leitner, Sabine Helbich, Thomas Hörnig, Mathias Helbich, Thomas H affil: Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20 1090 Vienna Austria sug: subj: Neoplasms, Ductal, Lobular, and Medullary Breast Neoplasms Granuloma Fibrocystic Disease of Breast Radiographic Image Enhancement Methods Carcinoma, Ductal, Breast Artifacts Contrast Media Image Processing, Computer Assisted Methods Female Aged Algorithms Pilot Studies Breast Middle Age Neoplasms, Fibrous Tissue Adult Sensitivity and Specificity Mammography Methods Electrodes Image Enhancement Human Aged: 65+ years Middle Aged: 45-64 years Adult: 19-44 years Female ab: Objectives: To demonstrate the feasibility of contrast-enhanced dual-energy mammography (CEDEM) using titanium (Ti) filtering at 49 kVp for high-energy images and a novel artefact reducing image-subtraction post-processing algorithm.Methods: Fifteen patients with suspicious findings (ACR BI-RADS 4 and 5) detected with digital mammography (MG) that required biopsy were included. CEDEM examinations were performed on a modified prototype machine. Acquired HE and low-energy raw data images were registered non-rigidly to compensate for possible subtle tissue motion. Subtracted CEDEM images were generated via weighted subtraction, using a fully automatic, locally adjusted tissue thickness-dependent subtraction factor to avoid over-subtraction at the breast border. Two observers evaluated the MG and CEDEM images according to ACR BI-RADS in two reading sessions. Results were correlated with histopathology.Results: Seven patients with benign and eight with malignant findings were included. All malignant lesions showed a strong contrast enhancement. BI-RADS assessment was altered in 66.6 % through the addition of CEDEM, resulting in increased overall accuracy. With CEDEM, additional lesions were depicted and false-positive rate was reduced compared to MG.Conclusions: CEDEM using Ti filtering with 49 kVp for HE exposures is feasible in a clinical setting. The proposed image-processing algorithm has the potential to reduce artefacts and improve CEDEM images.Key Points: • CEDEM with a titanium filter is feasible in a clinical setting. • Breast thickness-dependent image subtraction has the potential to improve CEDEM images. • The proposed image-processing algorithm reduces artefacts. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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