Determination of Death: A Scientific Perspective on Biological Integration.

Human life is operationally defined by the onset and cessation of organismal function. At postnatal stages of life, organismal integration critically and uniquely requires a functioning brain. In this article, a distinction is drawn between integrated and coordinated biologic activities. While commu...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Medicine & Philosophy Vol. 41; no. 3; pp. 257 - 279
Autor principal: CONDIC, MAUREEN L.
Formato: Journal Article
Publicado: Oxford University Press / USA Jun2016
Materias:
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=115352398&site=ehost-live
header:
  @attributes:
    shortDbName: hlh
    uiTerm: 115352398
    longDbName: Humanities International Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    jinfo:
      jid:
        03605310
        MPS
      jtl: Journal of Medicine & Philosophy
      issn: 03605310
      maglogo: N
    pubinfo:
      dt: Jun2016
      vid: 41
      iid: 3
      pid: 622
      pub: Oxford University Press / USA
    artinfo:
      ui:
        115352398
        10.1093/jmp/jhw004
      ppf: 257
      ppct: 22
      formats:
        fmt:
          @attributes:
            type: P
            size: 2MB
      tig:
        atl: Determination of Death: A Scientific Perspective on Biological Integration.
      aug:
        au: CONDIC, MAUREEN L.
        affil: University of Utah, Salt Lake City, Utah, USA
      su:
        Proof & certification of death
        Brain death
        Persistent vegetative state
        Brain function localization
        Vital signs
      sug:
        subj:
          Proof & certification of death
          Brain death
          Persistent vegetative state
          Brain function localization
          Vital signs
      keyword:
        brain death
        capacity for rationality
        determination of death
        organismal function
        persistent vegetative state
      ab: Human life is operationally defined by the onset and cessation of organismal function. At postnatal stages of life, organismal integration critically and uniquely requires a functioning brain. In this article, a distinction is drawn between integrated and coordinated biologic activities. While communication between cells can provide a coordinated biologic response to specific signals, it does not support the integrated function that is characteristic of a living human being. Determining the loss of integrated function can be complicated by medical interventions (i.e., "life support") that uncouple elements of the natural biologic hierarchy underlying our intuitive understanding of death. Such medical interventions can allow living human beings who are no longer able to function in an integrated manner to be maintained in a living state. In contrast, medical intervention can also allow the cells and tissues of an individual who has died to be maintained in a living state. To distinguish between a living human being and living human cells, two criteria are proposed: either the persistence of any form of brain function or the persistence of autonomous integration of vital functions. Either of these criteria is sufficient to determine a human being is alive.
      pubtype: Academic Journal
      doctype: Journal Article
      src: R
    language: English
    refInfo:
    copyright:
      @attributes:
        flag: Y
      custom: © 2019 Journal of Medicine and Philosophy Inc..
      item: Journal of Medicine & Philosophy
      holder: Oxford University Press / USA
      dt:
        @attributes:
          year: 2016
    holdings:
      @attributes:
        islocal: N