Neural Function Before and After Mindfulness-Based Cognitive Therapy in Anxious Adolescents at Risk for Developing Bipolar Disorder.
Objective: We sought to evaluate the neurophysiology of mindfulness-based cognitive therapy for children (MBCT-C) in youth with generalized, social, and/or separation anxiety disorder who were at risk for developing bipolar disorder.Methods: Nine youth (mean age: 13 ± 2 years) with a generalized, so...
| Publicado en: | Journal of Child & Adolescent Psychopharmacology Vol. 26; no. 4; pp. 372 - 380 |
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| Autores principales: | , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
May2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=115397892&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 115397892 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10445463 C1K jtl: Journal of Child & Adolescent Psychopharmacology issn: 10445463 maglogo: N pubinfo: dt: May2016 vid: 26 iid: 4 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 115397892 115397892 NLM26783833 115397892 10.1089/cap.2015.0054 NLM26783833 PMC4876535 [Available on 05/01/17] 115397892 ppf: 372 ppct: 8 formats: tig: atl: Neural Function Before and After Mindfulness-Based Cognitive Therapy in Anxious Adolescents at Risk for Developing Bipolar Disorder. aug: au: Strawn, Jeffrey R. Cotton, Sian Luberto, Christina M. Patino, L. Rodrigo Stahl, Lauren A. Weber, Wade A. Eliassen, James C. Sears, Richard DelBello, Melissa P. affil: Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, Ohio. sug: subj: Mindfulness Methods Anxiety Disorders Therapy Cognitive Therapy Methods Bipolar Disorder Prevention and Control Neuropsychological Tests Anxiety Disorders Psychosocial Factors Female Child Magnetic Resonance Imaging Prospective Studies Treatment Outcomes Risk Factors Brain Adolescence Male Clinical Assessment Tools Funding Source Human Child: 6-12 years Adolescent: 13-18 years Female Male ab: Objective: We sought to evaluate the neurophysiology of mindfulness-based cognitive therapy for children (MBCT-C) in youth with generalized, social, and/or separation anxiety disorder who were at risk for developing bipolar disorder.Methods: Nine youth (mean age: 13 ± 2 years) with a generalized, social, and/or separation anxiety disorder and a parent with bipolar disorder completed functional magnetic resonance imaging (fMRI) while performing a continuous processing task with emotional and neutral distractors (CPT-END) prior to and following 12 weeks of MBCT-C.Results: MBCT-C was associated with increases in activation of the bilateral insula, lentiform nucleus, and thalamus, as well as the left anterior cingulate while viewing emotional stimuli during the CPT-END, and decreases in anxiety were correlated with change in activation in the bilateral insula and anterior cingulate during the viewing of emotional stimuli (p < 0.05, uncorrected; p < 0.005 corrected; cluster size, 37 voxels).Conclusions: MBCT-C treatment in anxious youth with a familial history of bipolar disorder is associated with increased activation of brain structures that subserve interoception and the processing of internal stimuli-functions that are ostensibly improved by this treatment. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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